Cargando…

Targeting the Zinc Transporter ZIP7 in the Treatment of Insulin Resistance and Type 2 Diabetes

Type 2 diabetes mellitus (T2DM) is a disease associated with dysfunctional metabolic processes that lead to abnormally high levels of blood glucose. Preceding the development of T2DM is insulin resistance (IR), a disorder associated with suppressed or delayed responses to insulin. The effects of thi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Adulcikas, John, Sonda, Sabrina, Norouzi, Shaghayegh, Sohal, Sukhwinder Singh, Myers, Stephen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412268/ https://www.ncbi.nlm.nih.gov/pubmed/30781350 http://dx.doi.org/10.3390/nu11020408

Ejemplares similares

The Zinc Transporter Zip7 Is Downregulated in Skeletal Muscle of Insulin-Resistant Cells and in Mice Fed a High-Fat Diet
por: Norouzi, Shaghayegh, et al.
Publicado: (2019)

Zinc transporters and insulin resistance: therapeutic implications for type 2 diabetes and metabolic disease
por: Norouzi, Shaghayegh, et al.
Publicado: (2017)

Zinc stimulates glucose oxidation and glycemic control by modulating the insulin signaling pathway in human and mouse skeletal muscle cell lines
por: Norouzi, Shaghayegh, et al.
Publicado: (2018)

Zinc Modulates Several Transcription-Factor Regulated Pathways in Mouse Skeletal Muscle Cells
por: Vahidi Ferdowsi, Parisa, et al.
Publicado: (2020)

The Zinc Transporter, Slc39a7 (Zip7) Is Implicated in Glycaemic Control in Skeletal Muscle Cells
por: Myers, Stephen A., et al.
Publicado: (2013)

Different Actions of Intracellular Zinc Transporters ZIP7 and ZIP13 Are Essential for Dermal Development
por: Lee, Mi-Gi, et al.
Publicado: (2019)

Zinc transporter ZIP7 is a novel determinant of ferroptosis
por: Chen, Po-Han, et al.
Publicado: (2021)

Activated zinc transporter ZIP7 as an indicator of anti-hormone resistance in breast cancer
por: Ziliotto, Silvia, et al.
Publicado: (2019)

Pan-Domain Analysis of ZIP Zinc Transporters
por: Lehtovirta-Morley, Laura E., et al.
Publicado: (2017)

Heterogeneous Immunolocalisation of Zinc Transporters ZIP6, ZIP10 and ZIP14 in Human Normo- and Asthenozoospermic Spermatozoa
por: Protic, Isidora, et al.
Publicado: (2022)

Characterization of Zinc Influx Transporters (ZIPs) in Pancreatic β Cells: ROLES IN REGULATING CYTOSOLIC ZINC HOMEOSTASIS AND INSULIN SECRETION
por: Liu, Ying, et al.
Publicado: (2015)

hZIP1 zinc uptake transporter down regulation and zinc depletion in prostate cancer
por: Franklin, Renty B, et al.
Publicado: (2005)

Structural mechanism of intracellular autoregulation of zinc uptake in ZIP transporters
por: Pang, Changxu, et al.
Publicado: (2023)

Function, Structure, and Transport Aspects of ZIP and ZnT Zinc Transporters in Immune Cells
por: Bin, Bum-Ho, et al.
Publicado: (2018)

MTF-1-Mediated Repression of the Zinc Transporter Zip10 Is Alleviated by Zinc Restriction
por: Lichten, Louis A., et al.
Publicado: (2011)

hZip2 and hZip3 zinc transporters are down regulated in human prostate adenocarcinomatous glands
por: Desouki, Mohamed M, et al.
Publicado: (2007)

Zinc- and bicarbonate-dependent ZIP8 transporter mediates selenite uptake
por: McDermott, Joseph R., et al.
Publicado: (2016)

The two-domain elevator-type mechanism of zinc-transporting ZIP proteins
por: Wiuf, Anders, et al.
Publicado: (2022)

Zinc transporter ZIP10 forms a heteromer with ZIP6 which regulates embryonic development and cell migration
por: Taylor, Kathryn M., et al.
Publicado: (2016)

Zinc uptake promotes myoblast differentiation via Zip7 transporter and activation of Akt signalling transduction pathway
por: Mnatsakanyan, Hayk, et al.
Publicado: (2018)

Zinc Transporter SLC39A7/ZIP7 Promotes Intestinal Epithelial Self-Renewal by Resolving ER Stress
por: Ohashi, Wakana, et al.
Publicado: (2016)

Zinc Transporters and Zinc Signaling: New Insights into Their Role in Type 2 Diabetes
por: Myers, Stephen A.
Publicado: (2015)

Modeling Regulation of Zinc Uptake via ZIP Transporters in Yeast and Plant Roots
por: Claus, Juliane, et al.
Publicado: (2012)

Recent Advances in the Role of SLC39A/ZIP Zinc Transporters In Vivo
por: Takagishi, Teruhisa, et al.
Publicado: (2017)

The zinc transporter, ZIP12, regulates the pulmonary vascular response to chronic hypoxia
por: Zhao, Lan, et al.
Publicado: (2015)

Structural insights of ZIP4 extracellular domain critical for optimal zinc transport
por: Zhang, Tuo, et al.
Publicado: (2016)

Loss of zinc transporters ZIP1 and ZIP3 augments platelet reactivity in response to thrombin and accelerates thrombus formation in vivo
por: Elgheznawy, Amro, et al.
Publicado: (2023)

A role for the Drosophila zinc transporter Zip88E in protecting against dietary zinc toxicity
por: Richards, Christopher D., et al.
Publicado: (2017)

Capsaicin and Zinc Signalling Pathways as Promising Targets for Managing Insulin Resistance and Type 2 Diabetes
por: Ferdowsi, Parisa Vahidi, et al.
Publicado: (2023)

Zip4 Mediated Zinc Influx Stimulates Insulin Secretion in Pancreatic Beta Cells
por: Hardy, Alexandre B., et al.
Publicado: (2015)

The ZIP6/ZIP10 heteromer is essential for the zinc-mediated trigger of mitosis
por: Nimmanon, Thirayost, et al.
Publicado: (2020)

Genome-wide investigation of ZINC-IRON PERMEASE (ZIP) genes in Areca catechu and potential roles of ZIPs in Fe and Zn uptake and transport
por: An, Qiyuan, et al.
Publicado: (2021)

Crystal structures of a ZIP zinc transporter reveal a binuclear metal center in the transport pathway
por: Zhang, Tuo, et al.
Publicado: (2017)

OsNAC15 Regulates Tolerance to Zinc Deficiency and Cadmium by Binding to OsZIP7 and OsZIP10 in Rice
por: Zhan, Junhui, et al.
Publicado: (2022)

Zinc transporter ZIP12 maintains zinc homeostasis and protects spermatogonia from oxidative stress during spermatogenesis
por: Zhu, Xinye, et al.
Publicado: (2022)

Spondylocheirodysplastic Ehlers-Danlos syndrome (SCD-EDS) and the mutant zinc transporter ZIP13
por: Bin, Bum-Ho, et al.
Publicado: (2014)

Loss of the dermis zinc transporter ZIP13 promotes the mildness of fibrosarcoma by inhibiting autophagy
por: Lee, Mi-Gi, et al.
Publicado: (2019)

Overproduction of Human Zip (SLC39) Zinc Transporters in Saccharomyces cerevisiae for Biophysical Characterization
por: Becares, Eva Ramos, et al.
Publicado: (2021)

Deficiency in the zinc transporter ZIP8 impairs epithelia renewal and enhances lung fibrosis
por: Foster, Paul S., et al.
Publicado: (2022)

The Zinc Transporter Zip5 (Slc39a5) Regulates Intestinal Zinc Excretion and Protects the Pancreas against Zinc Toxicity
por: Geiser, Jim, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_9252oha3ejk09ci6e5i06ic2sj