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Free Accessible Databases as a Source of Information about Food Components and Other Compounds with Anticancer Activity–Brief Review
Diet is considered to be a significant factor in cancer prevention and therapy. Many food components reveal anticancer activity. The increasing number of experiments concerning the anticancer potential of chemical compounds, including food components, is a challenge for data searching. Specialized d...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412331/ https://www.ncbi.nlm.nih.gov/pubmed/30813234 http://dx.doi.org/10.3390/molecules24040789 |
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author | Minkiewicz, Piotr Turło, Marta Iwaniak, Anna Darewicz, Małgorzata |
author_facet | Minkiewicz, Piotr Turło, Marta Iwaniak, Anna Darewicz, Małgorzata |
author_sort | Minkiewicz, Piotr |
collection | PubMed |
description | Diet is considered to be a significant factor in cancer prevention and therapy. Many food components reveal anticancer activity. The increasing number of experiments concerning the anticancer potential of chemical compounds, including food components, is a challenge for data searching. Specialized databases provide an opportunity to overcome this problem. Data concerning the anticancer activity of chemical compounds may be found in general databases of chemical compounds and databases of drugs, including specialized resources concerning anticancer compounds, databases of food components, and databases of individual groups of compounds, such as polyphenols or peptides. This brief review summarizes the state of knowledge of chemical databases containing information concerning natural anticancer compounds (e.g., from food). Additionally, the information about text- and structure-based search options and links between particular internet resources is provided in this paper. Examples of the application of databases in food and nutrition sciences are also presented with special attention to compounds that are interesting from the point of view of dietary cancer prevention. Simple examples of potential database search possibilities are also discussed. |
format | Online Article Text |
id | pubmed-6412331 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-64123312019-04-09 Free Accessible Databases as a Source of Information about Food Components and Other Compounds with Anticancer Activity–Brief Review Minkiewicz, Piotr Turło, Marta Iwaniak, Anna Darewicz, Małgorzata Molecules Review Diet is considered to be a significant factor in cancer prevention and therapy. Many food components reveal anticancer activity. The increasing number of experiments concerning the anticancer potential of chemical compounds, including food components, is a challenge for data searching. Specialized databases provide an opportunity to overcome this problem. Data concerning the anticancer activity of chemical compounds may be found in general databases of chemical compounds and databases of drugs, including specialized resources concerning anticancer compounds, databases of food components, and databases of individual groups of compounds, such as polyphenols or peptides. This brief review summarizes the state of knowledge of chemical databases containing information concerning natural anticancer compounds (e.g., from food). Additionally, the information about text- and structure-based search options and links between particular internet resources is provided in this paper. Examples of the application of databases in food and nutrition sciences are also presented with special attention to compounds that are interesting from the point of view of dietary cancer prevention. Simple examples of potential database search possibilities are also discussed. MDPI 2019-02-22 /pmc/articles/PMC6412331/ /pubmed/30813234 http://dx.doi.org/10.3390/molecules24040789 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Minkiewicz, Piotr Turło, Marta Iwaniak, Anna Darewicz, Małgorzata Free Accessible Databases as a Source of Information about Food Components and Other Compounds with Anticancer Activity–Brief Review |
title | Free Accessible Databases as a Source of Information about Food Components and Other Compounds with Anticancer Activity–Brief Review |
title_full | Free Accessible Databases as a Source of Information about Food Components and Other Compounds with Anticancer Activity–Brief Review |
title_fullStr | Free Accessible Databases as a Source of Information about Food Components and Other Compounds with Anticancer Activity–Brief Review |
title_full_unstemmed | Free Accessible Databases as a Source of Information about Food Components and Other Compounds with Anticancer Activity–Brief Review |
title_short | Free Accessible Databases as a Source of Information about Food Components and Other Compounds with Anticancer Activity–Brief Review |
title_sort | free accessible databases as a source of information about food components and other compounds with anticancer activity–brief review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412331/ https://www.ncbi.nlm.nih.gov/pubmed/30813234 http://dx.doi.org/10.3390/molecules24040789 |
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