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Free Accessible Databases as a Source of Information about Food Components and Other Compounds with Anticancer Activity–Brief Review

Diet is considered to be a significant factor in cancer prevention and therapy. Many food components reveal anticancer activity. The increasing number of experiments concerning the anticancer potential of chemical compounds, including food components, is a challenge for data searching. Specialized d...

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Detalles Bibliográficos
Autores principales: Minkiewicz, Piotr, Turło, Marta, Iwaniak, Anna, Darewicz, Małgorzata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412331/
https://www.ncbi.nlm.nih.gov/pubmed/30813234
http://dx.doi.org/10.3390/molecules24040789
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author Minkiewicz, Piotr
Turło, Marta
Iwaniak, Anna
Darewicz, Małgorzata
author_facet Minkiewicz, Piotr
Turło, Marta
Iwaniak, Anna
Darewicz, Małgorzata
author_sort Minkiewicz, Piotr
collection PubMed
description Diet is considered to be a significant factor in cancer prevention and therapy. Many food components reveal anticancer activity. The increasing number of experiments concerning the anticancer potential of chemical compounds, including food components, is a challenge for data searching. Specialized databases provide an opportunity to overcome this problem. Data concerning the anticancer activity of chemical compounds may be found in general databases of chemical compounds and databases of drugs, including specialized resources concerning anticancer compounds, databases of food components, and databases of individual groups of compounds, such as polyphenols or peptides. This brief review summarizes the state of knowledge of chemical databases containing information concerning natural anticancer compounds (e.g., from food). Additionally, the information about text- and structure-based search options and links between particular internet resources is provided in this paper. Examples of the application of databases in food and nutrition sciences are also presented with special attention to compounds that are interesting from the point of view of dietary cancer prevention. Simple examples of potential database search possibilities are also discussed.
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spelling pubmed-64123312019-04-09 Free Accessible Databases as a Source of Information about Food Components and Other Compounds with Anticancer Activity–Brief Review Minkiewicz, Piotr Turło, Marta Iwaniak, Anna Darewicz, Małgorzata Molecules Review Diet is considered to be a significant factor in cancer prevention and therapy. Many food components reveal anticancer activity. The increasing number of experiments concerning the anticancer potential of chemical compounds, including food components, is a challenge for data searching. Specialized databases provide an opportunity to overcome this problem. Data concerning the anticancer activity of chemical compounds may be found in general databases of chemical compounds and databases of drugs, including specialized resources concerning anticancer compounds, databases of food components, and databases of individual groups of compounds, such as polyphenols or peptides. This brief review summarizes the state of knowledge of chemical databases containing information concerning natural anticancer compounds (e.g., from food). Additionally, the information about text- and structure-based search options and links between particular internet resources is provided in this paper. Examples of the application of databases in food and nutrition sciences are also presented with special attention to compounds that are interesting from the point of view of dietary cancer prevention. Simple examples of potential database search possibilities are also discussed. MDPI 2019-02-22 /pmc/articles/PMC6412331/ /pubmed/30813234 http://dx.doi.org/10.3390/molecules24040789 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Minkiewicz, Piotr
Turło, Marta
Iwaniak, Anna
Darewicz, Małgorzata
Free Accessible Databases as a Source of Information about Food Components and Other Compounds with Anticancer Activity–Brief Review
title Free Accessible Databases as a Source of Information about Food Components and Other Compounds with Anticancer Activity–Brief Review
title_full Free Accessible Databases as a Source of Information about Food Components and Other Compounds with Anticancer Activity–Brief Review
title_fullStr Free Accessible Databases as a Source of Information about Food Components and Other Compounds with Anticancer Activity–Brief Review
title_full_unstemmed Free Accessible Databases as a Source of Information about Food Components and Other Compounds with Anticancer Activity–Brief Review
title_short Free Accessible Databases as a Source of Information about Food Components and Other Compounds with Anticancer Activity–Brief Review
title_sort free accessible databases as a source of information about food components and other compounds with anticancer activity–brief review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412331/
https://www.ncbi.nlm.nih.gov/pubmed/30813234
http://dx.doi.org/10.3390/molecules24040789
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