Cargando…

Multicharged Phthalocyanines as Selective Ligands for G-Quadruplex DNA Structures

The stabilization of G-Quadruplex DNA structures by ligands is a promising strategy for telomerase inhibition in cancer therapy since this enzyme is responsible for the unlimited proliferation of cancer cells. To assess the potential of a compound as a telomerase inhibitor, selectivity for quadruple...

Descripción completa

Detalles Bibliográficos
Autores principales: Ramos, Catarina I. V., Almeida, Susana P., Lourenço, Leandro M. O., Pereira, Patrícia M. R., Fernandes, Rosa, Faustino, M. Amparo F., Tomé, João P. C., Carvalho, Josué, Cruz, Carla, Neves, M. Graça P. M. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412362/
https://www.ncbi.nlm.nih.gov/pubmed/30781675
http://dx.doi.org/10.3390/molecules24040733

Ejemplares similares