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Bioactivity Determination of a Therapeutic Recombinant Human Keratinocyte Growth Factor by a Validated Cell-based Bioassay
The therapeutic recombinant human keratinocyte growth factor 1 (rhKGF-1) was approved by the FDA for oral mucositis resulting from hematopoietic stem cell transplantation for hematological malignancies in 2004. However, no recommended bioassay for rhKGF-1 bioactivity has been recorded in the U.S. Ph...
Autores principales: | Yao, Wenrong, Guo, Ying, Qin, Xi, Yu, Lei, Shi, Xinchang, Liu, Lan, Zhou, Yong, Hu, Jinpan, Rao, Chunming, Wang, Junzhi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412437/ https://www.ncbi.nlm.nih.gov/pubmed/30769959 http://dx.doi.org/10.3390/molecules24040699 |
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