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Glucagon-Like Peptide-1 (GLP-1) and 5-Hydroxytryptamine 2c (5-HT(2c)) Receptor Agonists in the Ventral Tegmental Area (VTA) Inhibit Ghrelin-Stimulated Appetitive Reward
Current literature indicates that the orexigenic peptide ghrelin increases appetitive motivation via signaling in the mesolimbic reward system. Another gastric peptide, glucagon-like peptide-1 (GLP-1), and the neurotransmitter 5-hydroxytryptamine (5-HT), are both known to suppress operant responding...
Autores principales: | Howell, Erin, Baumgartner, Hannah M., Zallar, Lia J., Selva, Joaquín A., Engel, Liv, Currie, Paul J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412472/ https://www.ncbi.nlm.nih.gov/pubmed/30791361 http://dx.doi.org/10.3390/ijms20040889 |
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