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Long-Term Diabetic Microenvironment Augments the Decay Rate of Capsaicin-Induced Currents in Mouse Dorsal Root Ganglion Neurons

Individuals with end-stage diabetic peripheral neuropathy present with decreased pain sensation. Transient receptor potential vanilloid type 1 (TRPV1) is implicated in pain signaling and resides on sensory dorsal root ganglion (DRG) neurons. We investigated the expression and functional activity of...

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Detalles Bibliográficos
Autores principales: Chen, Xingjuan, Duan, Yaqian, Riley, Ashley M., Welch, Megan A., White, Fletcher A., Grant, Maria B., Obukhov, Alexander G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412516/
https://www.ncbi.nlm.nih.gov/pubmed/30795543
http://dx.doi.org/10.3390/molecules24040775