Cargando…

Dissecting Intra-Tumor Heterogeneity by the Analysis of Copy Number Variations in Single Cells: The Neuroblastoma Case Study

Tumors often show intra-tumor heterogeneity because of genotypic differences between all the cells that compose it and that derive from it. Recent studies have shown significant aspects of neuroblastoma heterogeneity that may affect the diagnostic-therapeutic strategy. Therefore, we developed a labo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cariati, Federica, Borrillo, Francesca, Shankar, Varun, Nunziato, Marcella, D’Argenio, Valeria, Tomaiuolo, Rossella
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Technical Note
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412524/ https://www.ncbi.nlm.nih.gov/pubmed/30791380 http://dx.doi.org/10.3390/ijms20040893

Ejemplares similares

The evolving role of genetic tests in reproductive medicine
por: Cariati, Federica, et al.
Publicado: (2019)

One4Two(®): An Integrated Molecular Approach to Optimize Infertile Couples’ Journey
por: D’Argenio, Valeria, et al.
Publicado: (2021)

Microbiota and Human Reproduction: The Case of Male Infertility
por: Tomaiuolo, Rossella, et al.
Publicado: (2020)

Microbiota and Human Reproduction: The Case of Female Infertility
por: Tomaiuolo, Rossella, et al.
Publicado: (2020)

From laboratory bench to benchmark: technology transfer in laboratory medicine
por: Cariati, Federica, et al.
Publicado: (2020)

Metagenomics Reveals Specific Microbial Features in Males with Semen Alterations
por: Veneruso, Iolanda, et al.
Publicado: (2023)

“Bisphenol a: an emerging threat to male fertility”
por: Cariati, Federica, et al.
Publicado: (2019)

Current Updates on Expanded Carrier Screening: New Insights in the Omics Era
por: Veneruso, Iolanda, et al.
Publicado: (2022)

Unraveling the Balance between Genes, Microbes, Lifestyle and the Environment to Improve Healthy Reproduction
por: D’Argenio, Valeria, et al.
Publicado: (2021)

Comprehensive Molecular Analysis of DMD Gene Increases the Diagnostic Value of Dystrophinopathies: A Pilot Study in a Southern Italy Cohort of Patients
por: De Palma, Fatima Domenica Elisa, et al.
Publicado: (2021)

A Familial Novel Putative-Pathogenic Mutation Identified in Plaque-Psoriasis by a Multigene Panel Analysis
por: Nunziato, Marcella, et al.
Publicado: (2023)

Genotype-Phenotype Correlation: A Triple DNA Mutational Event in a Boy Entering Sport Conveys an Additional Pathogenicity Risk
por: Limongelli, Giuseppe, et al.
Publicado: (2020)

Microbiological Evaluation and Sperm DNA Fragmentation in Semen Samples of Patients Undergoing Fertility Investigation
por: Pagliuca, Chiara, et al.
Publicado: (2021)

Microbiome composition indicate dysbiosis and lower richness in tumor breast tissues compared to healthy adjacent paired tissue, within the same women
por: Esposito, Maria Valeria, et al.
Publicado: (2022)

CopyDetective: Detection threshold–aware copy number variant calling in whole-exome sequencing data
por: Sandmann, Sarah, et al.
Publicado: (2020)

FocalCall: An R Package for the Annotation of Focal Copy Number Aberrations
por: Krijgsman, Oscar, et al.
Publicado: (2014)

Fast Detection of a BRCA2 Large Genomic Duplication by Next Generation Sequencing as a Single Procedure: A Case Report
por: Nunziato, Marcella, et al.
Publicado: (2017)

A Novel Pathogenic BRCA1 Splicing Variant Produces Partial Intron Retention in the Mature Messenger RNA
por: Esposito, Maria Valeria, et al.
Publicado: (2016)

Multi-gene panel testing increases germline predisposing mutations’ detection in a cohort of breast/ovarian cancer patients from Southern Italy
por: Nunziato, Marcella, et al.
Publicado: (2022)

Concurrent Measurement of Mitochondrial DNA Copy Number and ATP Concentration in Single Bovine Oocytes
por: Read, Casey C., et al.
Publicado: (2021)

V-shaped lymph node dissection in laparoscopic distal gastrectomy; new technique of intra-abdominal dissection and surgical outcomes
por: Matsuhashi, Nobuhisa, et al.
Publicado: (2012)

The High-Throughput Analyses Era: Are We Ready for the Data Struggle?
por: D’Argenio, Valeria
Publicado: (2018)

Human Microbiome Acquisition and Bioinformatic Challenges in Metagenomic Studies
por: D’Argenio, Valeria
Publicado: (2018)

The Prenatal Microbiome: A New Player for Human Health
por: D’Argenio, Valeria
Publicado: (2018)

Rapid and reliable detection of α-globin copy number variations by quantitative real-time PCR
por: Grimholt, Runa M, et al.
Publicado: (2014)

CNVcaller: highly efficient and widely applicable software for detecting copy number variations in large populations
por: Wang, Xihong, et al.
Publicado: (2017)

Variable Copy Number, Intra-Genomic Heterogeneities and Lateral Transfers of the 16S rRNA Gene in Pseudomonas
por: Bodilis, Josselin, et al.
Publicado: (2012)

Celiac disease‐associated Neisseria flavescens decreases mitochondrial respiration in CaCo‐2 epithelial cells: Impact of Lactobacillus paracasei CBA L74 on bacterial‐induced cellular imbalance
por: Labruna, Giuseppe, et al.
Publicado: (2019)

Meta-mining of copy number profiles of high-risk neuroblastoma tumors
por: Depuydt, Pauline, et al.
Publicado: (2018)

Quantifying mitochondrial DNA copy number using robust regression to interpret real time PCR results
por: Refinetti, Paulo, et al.
Publicado: (2017)

Copy Number Heterogeneity of JC Virus Standards
por: Greninger, Alexander L., et al.
Publicado: (2017)

Clinical analysis of germline copy number variation in DMD using a non-conjugate hierarchical Bayesian model
por: Kozareva, Velina, et al.
Publicado: (2018)

Intra-Tumour Genetic Heterogeneity and Prognosis in High-Risk Neuroblastoma
por: López-Carrasco, Amparo, et al.
Publicado: (2021)

SNPs and real-time quantitative PCR method for constitutional allelic copy number determination, the VPREB1 marker case
por: Frigerio, Marcello, et al.
Publicado: (2011)

High quality copy number and genotype data from FFPE samples using Molecular Inversion Probe (MIP) microarrays
por: Wang, Yuker, et al.
Publicado: (2009)

Focal DNA Copy Number Changes in Neuroblastoma Target MYCN Regulated Genes
por: Kumps, Candy, et al.
Publicado: (2013)

Chronic radiation exposure of neuroblastoma cells reduces nMYC copy number
por: Gnanamony, Manu, et al.
Publicado: (2017)

New Insights into the Molecular Bases of Familial Alzheimer’s Disease
por: D’Argenio, Valeria, et al.
Publicado: (2020)

Microbiome Influence in the Pathogenesis of Prion and Alzheimer’s Diseases
por: D’Argenio, Valeria, et al.
Publicado: (2019)

Probiotics, prebiotics and their role in Alzheimer’s disease
por: D'Argenio, Valeria, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_0c7qnpj6fmp6q390ote6e33j87