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Association between Nutritional Status and Mortality after Aortic Valve Replacement Procedure in Elderly with Severe Aortic Stenosis

Background: There is still a lack of data on the nutritional status of older people with aortic stenosis (AS) and the effect of poor nutrition on the occurrence of complications and mortality after an aortic valve replacement (AVR) procedure. The aim of this study was to assess the impact of selecte...

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Autores principales: Wernio, Edyta, Małgorzewicz, Sylwia, Dardzińska, Jolanta Anna, Jagielak, Dariusz, Rogowski, Jan, Gruszecka, Agnieszka, Klapkowski, Andrzej, Bramlage, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412537/
https://www.ncbi.nlm.nih.gov/pubmed/30791677
http://dx.doi.org/10.3390/nu11020446
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author Wernio, Edyta
Małgorzewicz, Sylwia
Dardzińska, Jolanta Anna
Jagielak, Dariusz
Rogowski, Jan
Gruszecka, Agnieszka
Klapkowski, Andrzej
Bramlage, Peter
author_facet Wernio, Edyta
Małgorzewicz, Sylwia
Dardzińska, Jolanta Anna
Jagielak, Dariusz
Rogowski, Jan
Gruszecka, Agnieszka
Klapkowski, Andrzej
Bramlage, Peter
author_sort Wernio, Edyta
collection PubMed
description Background: There is still a lack of data on the nutritional status of older people with aortic stenosis (AS) and the effect of poor nutrition on the occurrence of complications and mortality after an aortic valve replacement (AVR) procedure. The aim of this study was to assess the impact of selected nutritional status parameters in elderly patients with severe AS on the occurrence of postoperative complications and one-year mortality after the AVR procedure. Methods: 101 elderly patients with AS aged 74.6 ± 5.2 years who qualified for surgical treatment (aortic valve area [AVA] 0.73 ± 0.2 cm(2)) were enrolled in the study. A nutritional status assessment was performed before AVR surgery, and the frequency of postoperative complications occurring within 30 days of surgery was assessed. The one-year mortality rate was also captured. Results: Adverse events (both major and minor) up to 30 days occurred in 49.5% (n = 50) of the study population. Low Mini Nutritional Assessment (f-MNA) and Subjective Global Assessment (7-SGA) scores and low concentrations of total cholesterol, LDL-cholesterol, and prealbumin were associated with a higher risk of postoperative complications. The risk of complications increased 1.22 times (95% CI; 1.030–1.453; p = 0.019) with an impaired nutritional status. The annual mortality rate in the study group was 7.9%. Unintentional weight loss of >2.8% in the six months preceding surgery proved useful for predicting death within the first year after AVR surgery. Conclusions: The results indicate that poor nutritional status is an important factor affecting the adverse outcomes in elderly patients with severe aortic valve stenosis undergoing an AVR procedure.
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spelling pubmed-64125372019-03-29 Association between Nutritional Status and Mortality after Aortic Valve Replacement Procedure in Elderly with Severe Aortic Stenosis Wernio, Edyta Małgorzewicz, Sylwia Dardzińska, Jolanta Anna Jagielak, Dariusz Rogowski, Jan Gruszecka, Agnieszka Klapkowski, Andrzej Bramlage, Peter Nutrients Article Background: There is still a lack of data on the nutritional status of older people with aortic stenosis (AS) and the effect of poor nutrition on the occurrence of complications and mortality after an aortic valve replacement (AVR) procedure. The aim of this study was to assess the impact of selected nutritional status parameters in elderly patients with severe AS on the occurrence of postoperative complications and one-year mortality after the AVR procedure. Methods: 101 elderly patients with AS aged 74.6 ± 5.2 years who qualified for surgical treatment (aortic valve area [AVA] 0.73 ± 0.2 cm(2)) were enrolled in the study. A nutritional status assessment was performed before AVR surgery, and the frequency of postoperative complications occurring within 30 days of surgery was assessed. The one-year mortality rate was also captured. Results: Adverse events (both major and minor) up to 30 days occurred in 49.5% (n = 50) of the study population. Low Mini Nutritional Assessment (f-MNA) and Subjective Global Assessment (7-SGA) scores and low concentrations of total cholesterol, LDL-cholesterol, and prealbumin were associated with a higher risk of postoperative complications. The risk of complications increased 1.22 times (95% CI; 1.030–1.453; p = 0.019) with an impaired nutritional status. The annual mortality rate in the study group was 7.9%. Unintentional weight loss of >2.8% in the six months preceding surgery proved useful for predicting death within the first year after AVR surgery. Conclusions: The results indicate that poor nutritional status is an important factor affecting the adverse outcomes in elderly patients with severe aortic valve stenosis undergoing an AVR procedure. MDPI 2019-02-20 /pmc/articles/PMC6412537/ /pubmed/30791677 http://dx.doi.org/10.3390/nu11020446 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Wernio, Edyta
Małgorzewicz, Sylwia
Dardzińska, Jolanta Anna
Jagielak, Dariusz
Rogowski, Jan
Gruszecka, Agnieszka
Klapkowski, Andrzej
Bramlage, Peter
Association between Nutritional Status and Mortality after Aortic Valve Replacement Procedure in Elderly with Severe Aortic Stenosis
title Association between Nutritional Status and Mortality after Aortic Valve Replacement Procedure in Elderly with Severe Aortic Stenosis
title_full Association between Nutritional Status and Mortality after Aortic Valve Replacement Procedure in Elderly with Severe Aortic Stenosis
title_fullStr Association between Nutritional Status and Mortality after Aortic Valve Replacement Procedure in Elderly with Severe Aortic Stenosis
title_full_unstemmed Association between Nutritional Status and Mortality after Aortic Valve Replacement Procedure in Elderly with Severe Aortic Stenosis
title_short Association between Nutritional Status and Mortality after Aortic Valve Replacement Procedure in Elderly with Severe Aortic Stenosis
title_sort association between nutritional status and mortality after aortic valve replacement procedure in elderly with severe aortic stenosis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412537/
https://www.ncbi.nlm.nih.gov/pubmed/30791677
http://dx.doi.org/10.3390/nu11020446
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