Discovery of Novel Acetylcholinesterase Inhibitors as Potential Candidates for the Treatment of Alzheimer’s Disease

Acetylcholinesterase (AChE) catalyzes the hydrolysis of neurotransmitter acetylcholine to acetate and choline in a synaptic cleft. Deficits in cholinergic neurotransmitters are linked closely with the progression of Alzheimer’s disease (AD), which is a neurodegenerative disorder characterized by mem...

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Detalles Bibliográficos
Autores principales: Son, Minky, Park, Chanin, Rampogu, Shailima, Zeb, Amir, Lee, Keun Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412560/
https://www.ncbi.nlm.nih.gov/pubmed/30823604
http://dx.doi.org/10.3390/ijms20041000

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412560/
https://www.ncbi.nlm.nih.gov/pubmed/30823604
http://dx.doi.org/10.3390/ijms20041000

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