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Discovery of Novel Acetylcholinesterase Inhibitors as Potential Candidates for the Treatment of Alzheimer’s Disease

Acetylcholinesterase (AChE) catalyzes the hydrolysis of neurotransmitter acetylcholine to acetate and choline in a synaptic cleft. Deficits in cholinergic neurotransmitters are linked closely with the progression of Alzheimer’s disease (AD), which is a neurodegenerative disorder characterized by mem...

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Detalles Bibliográficos
Autores principales:	Son, Minky, Park, Chanin, Rampogu, Shailima, Zeb, Amir, Lee, Keun Woo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412560/ https://www.ncbi.nlm.nih.gov/pubmed/30823604 http://dx.doi.org/10.3390/ijms20041000

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