Cargando…

Divergent Effectiveness of Multispecies Probiotic Preparations on Intestinal Microbiota Structure Depends on Metabolic Properties

A growing body of evidence suggests that probiotic functionality is not accurately predicted by their taxonomy. Here, we have set up a study to investigate the effectiveness of two probiotic formulations containing a blend of seven bacterial species in modulating intestinal inflammation in two roden...

Descripción completa

Detalles Bibliográficos
Autores principales:	Biagioli, Michele, Capobianco, Daniela, Carino, Adriana, Marchianò, Silvia, Fiorucci, Chiara, Ricci, Patrizia, Distrutti, Eleonora, Fiorucci, Stefano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412585/ https://www.ncbi.nlm.nih.gov/pubmed/30717413 http://dx.doi.org/10.3390/nu11020325

Ejemplares similares

Metabolic Variability of a Multispecies Probiotic Preparation Impacts on the Anti-inflammatory Activity
por: Biagioli, Michele, et al.
Publicado: (2017)

Discovery of a Novel Multi-Strains Probiotic Formulation with Improved Efficacy toward Intestinal Inflammation
por: Biagioli, Michele, et al.
Publicado: (2020)

Bile Acids Activated Receptors in Inflammatory Bowel Disease
por: Biagioli, Michele, et al.
Publicado: (2021)

Transcriptome Analysis of Dual FXR and GPBAR1 Agonism in Rodent Model of NASH Reveals Modulation of Lipid Droplets Formation
por: Carino, Adriana, et al.
Publicado: (2019)

GPBAR1 Functions as Gatekeeper for Liver NKT Cells and provides Counterregulatory Signals in Mouse Models of Immune-Mediated Hepatitis
por: Biagioli, Michele, et al.
Publicado: (2019)

Analysis of Gastric Cancer Transcriptome Allows the Identification of Histotype Specific Molecular Signatures With Prognostic Potential
por: Carino, Adriana, et al.
Publicado: (2021)

The Aryl Hydrocarbon Receptor (AhR) Mediates the Counter-Regulatory Effects of Pelargonidins in Models of Inflammation and Metabolic Dysfunctions
por: Biagioli, Michele, et al.
Publicado: (2019)

Bile Acid Signaling in Inflammatory Bowel Diseases
por: Fiorucci, Stefano, et al.
Publicado: (2020)

Bile Acids Activated Receptors Regulate Innate Immunity
por: Fiorucci, Stefano, et al.
Publicado: (2018)

Hijacking SARS-CoV-2/ACE2 Receptor Interaction by Natural and Semi-synthetic Steroidal Agents Acting on Functional Pockets on the Receptor Binding Domain
por: Carino, Adriana, et al.
Publicado: (2020)

Gpbar1 agonism promotes a Pgc-1α-dependent browning of white adipose tissue and energy expenditure and reverses diet-induced steatohepatitis in mice
por: Carino, Adriana, et al.
Publicado: (2017)

BAR502, a dual FXR and GPBAR1 agonist, promotes browning of white adipose tissue and reverses liver steatosis and fibrosis
por: Carino, Adriana, et al.
Publicado: (2017)

Probiotics Modulate Intestinal Expression of Nuclear Receptor and Provide Counter-Regulatory Signals to Inflammation-Driven Adipose Tissue Activation
por: Mencarelli, Andrea, et al.
Publicado: (2011)

Modulation of Intestinal Microbiota by the Probiotic VSL#3 Resets Brain Gene Expression and Ameliorates the Age-Related Deficit in LTP
por: Distrutti, Eleonora, et al.
Publicado: (2014)

Decoding the role of the nuclear receptor SHP in regulating hepatic stellate cells and liver fibrogenesis
por: Cipriani, Sabrina, et al.
Publicado: (2017)

Probiotics VSL#3 Protect against Development of Visceral Pain in Murine Model of Irritable Bowel Syndrome
por: Distrutti, Eleonora, et al.
Publicado: (2013)

The HIV matrix protein p17 induces hepatic lipid accumulation via modulation of nuclear receptor transcriptoma
por: Renga, Barbara, et al.
Publicado: (2015)

Discovery of a AHR pelargonidin agonist that counter-regulates Ace2 expression and attenuates ACE2-SARS-CoV-2 interaction
por: Biagioli, Michele, et al.
Publicado: (2021)

The Bile Acid Sensor FXR Is Required for Immune-Regulatory Activities of TLR-9 in Intestinal Inflammation
por: Renga, Barbara, et al.
Publicado: (2013)

Discovery of Bile Acid Derivatives as Potent ACE2 Activators by Virtual Screening and Essential Dynamics
por: Fiorillo, Bianca, et al.
Publicado: (2021)

GLP-1 Mediates Regulation of Colonic ACE2 Expression by the Bile Acid Receptor GPBAR1 in Inflammation
por: Biagioli, Michele, et al.
Publicado: (2022)

The bile acid receptor GPBAR1 (TGR5) is expressed in human gastric cancers and promotes epithelial-mesenchymal transition in gastric cancer cell lines
por: Carino, Adriana, et al.
Publicado: (2016)

Navigation in bile acid chemical space: discovery of novel FXR and GPBAR1 ligands
por: Finamore, Claudia, et al.
Publicado: (2016)

Combinatorial therapy with BAR502 and UDCA resets FXR and GPBAR1 signaling and reverses liver histopathology in a model of NASH
por: Marchianò, Silvia, et al.
Publicado: (2023)

Next-Generation Sequencing Analysis of Gastric Cancer Identifies the Leukemia Inhibitory Factor Receptor as a Driving Factor in Gastric Cancer Progression and as a Predictor of Poor Prognosis
por: Di Giorgio, Cristina, et al.
Publicado: (2022)

Targeting Bile Acid Receptors: Discovery of a Potent and Selective Farnesoid X Receptor Agonist as a New Lead in the Pharmacological Approach to Liver Diseases
por: Festa, Carmen, et al.
Publicado: (2017)

Discovery of BAR502, as potent steroidal antagonist of leukemia inhibitory factor receptor for the treatment of pancreatic adenocarcinoma
por: Di Giorgio, Cristina, et al.
Publicado: (2023)

VSL#3 Resets Insulin Signaling and Protects against NASH and Atherosclerosis in a Model of Genetic Dyslipidemia and Intestinal Inflammation
por: Mencarelli, Andrea, et al.
Publicado: (2012)

Repositioning Mifepristone as a Leukaemia Inhibitory Factor Receptor Antagonist for the Treatment of Pancreatic Adenocarcinoma
por: Di Giorgio, Cristina, et al.
Publicado: (2022)

Solomonsterol A, a Marine Pregnane-X-Receptor Agonist, Attenuates Inflammation and Immune Dysfunction in a Mouse Model of Arthritis
por: Mencarelli, Andrea, et al.
Publicado: (2013)

Reversal of Endothelial Dysfunction by GPBAR1 Agonism in Portal Hypertension Involves a AKT/FOXOA1 Dependent Regulation of H(2)S Generation and Endothelin-1
por: Renga, Barbara, et al.
Publicado: (2015)

The Bile Acid Receptor GPBAR-1 (TGR5) Modulates Integrity of Intestinal Barrier and Immune Response to Experimental Colitis
por: Cipriani, Sabrina, et al.
Publicado: (2011)

Dissociation of Intestinal and Hepatic Activities of FXR and LXRα Supports Metabolic Effects of Terminal Ileum Interposition in Rodents
por: Mencarelli, Andrea, et al.
Publicado: (2013)

Hydrogen sulphide induces μ opioid receptor-dependent analgesia in a rodent model of visceral pain
por: Distrutti, Eleonora, et al.
Publicado: (2010)

Correction: The Bile Acid Receptor GPBAR-1 (TGR5) Modulates Integrity of Intestinal Barrier and Immune Response to Experimental Colitis
por: Cipriani, Sabrina, et al.
Publicado: (2013)

Introduction of Nonacidic Side Chains on 6-Ethylcholane Scaffolds in the Identification of Potent Bile Acid Receptor Agonists with Improved Pharmacokinetic Properties
por: Finamore, Claudia, et al.
Publicado: (2019)

Highly specific blockade of CCR5 inhibits leukocyte trafficking and reduces mucosal inflammation in murine colitis
por: Mencarelli, Andrea, et al.
Publicado: (2016)

The Bile Acid Sensor FXR Protects against Dyslipidemia and Aortic Plaques Development Induced by the HIV Protease Inhibitor Ritonavir in Mice
por: Mencarelli, Andrea, et al.
Publicado: (2010)

Discovery of ((1,2,4-oxadiazol-5-yl)pyrrolidin-3-yl)ureidyl derivatives as selective non-steroidal agonists of the G-protein coupled bile acid receptor-1
por: Di Leva, Francesco Saverio, et al.
Publicado: (2019)

Nitric oxide protects against HIV gp120 endothelial injury
por: Fiorucci, S, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_26csgu6a8r4b05rqcqp45unt2f