Administration of DDAVP did not improve the pharmacokinetics of FVIII concentrate in a clinically significant manner

BACKGROUND: The half-life and mean residence time (MRT) of infused recombinant factor VIII (FVIII) concentrate are associated with pre-infusion levels of von Willebrand factor (VWF) in severely affected hemophilia A patients. It is currently unknown if individual FVIII concentrate half-life and MRT...

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Detalles Bibliográficos
Autores principales: Loomans, Janneke I, Stokhuijzen, Eva, Peters, Marjolein, Fijnvandraat, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Whioce Publishing Pte. Ltd. 2018
Materias:
Special Issue Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412613/
https://www.ncbi.nlm.nih.gov/pubmed/30873482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412613/
https://www.ncbi.nlm.nih.gov/pubmed/30873482

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