Ophthalmic acid as a read-out for hepatic glutathione metabolism in humans

BACKGROUND AND AIM: Animal studies indicated that systemic ophthalmic acid (OPH) is a biomarker for hepatic glutathione (GSH) homeostasis, an important determinant of liver function. We aimed to clarify whether OPH levels can be used as a read-out for hepatic GSH homeostasis after paracetamol (APAP)...

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Detalles Bibliográficos
Autores principales: Kim MC van, Mierlo, Dello, Simon AWG, de Jong, Mechteld C, van Eijk, Hans MH, de Kok, Theo M, Briedé, Jacob J, Schaap, Frank G, Damink, Steven WM Olde, Dejong, Cornelius HC
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Whioce Publishing Pte. Ltd. 2018
Materias:
Special Issue Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412618/
https://www.ncbi.nlm.nih.gov/pubmed/30873484

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