Four Major Channels Detected in the Cytochrome P450 3A4: A Step toward Understanding Its Multispecificity

We computed the network of channels of the 3A4 isoform of the cytochrome P450 (CYP) on the basis of 16 crystal structures extracted from the Protein Data Bank (PDB). The calculations were performed with version 2 of the CCCPP software that we developed for this research project. We identified the mi...

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Detalles Bibliográficos
Autores principales: Benkaidali, Lydia, André, François, Moroy, Gautier, Tangour, Bahoueddine, Maurel, François, Petitjean, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412807/
https://www.ncbi.nlm.nih.gov/pubmed/30823507
http://dx.doi.org/10.3390/ijms20040987

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412807/
https://www.ncbi.nlm.nih.gov/pubmed/30823507
http://dx.doi.org/10.3390/ijms20040987

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