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Four Major Channels Detected in the Cytochrome P450 3A4: A Step toward Understanding Its Multispecificity
We computed the network of channels of the 3A4 isoform of the cytochrome P450 (CYP) on the basis of 16 crystal structures extracted from the Protein Data Bank (PDB). The calculations were performed with version 2 of the CCCPP software that we developed for this research project. We identified the mi...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412807/ https://www.ncbi.nlm.nih.gov/pubmed/30823507 http://dx.doi.org/10.3390/ijms20040987 |