Cargando…

Identification and Evaluation of Inhibitors of Lipase from Malassezia restricta using Virtual High-Throughput Screening and Molecular Dynamics Studies

Recent studies revealed the role of lipase in the pathogenicity of Malassezia restricta in dandruff and seborrheic dermatitis (D/SD). The lipase from M. restricta (Mrlip1) is considered a potential target for dandruff therapy. In this work, we performed structure-based virtual screening in Zinc data...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ali, Shahid, Khan, Faez Iqbal, Mohammad, Taj, Lan, Dongming, Hassan, Md. Imtaiyaz, Wang, Yonghua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412828/ https://www.ncbi.nlm.nih.gov/pubmed/30781686 http://dx.doi.org/10.3390/ijms20040884

Ejemplares similares

Evaluation of Expression of Lipases and Phospholipases of Malassezia restricta in Patients with Seborrheic Dermatitis
por: Lee, Yang Won, et al.
Publicado: (2013)

Genotypic Analysis of the Population Structure in Malassezia globosa and Malassezia restricta
por: Hadrich, Ines, et al.
Publicado: (2023)

pH-Dependent Expression, Stability, and Activity of Malassezia restricta MrLip5 Lipase
por: Park, Minji, et al.
Publicado: (2020)

Resequencing the Genome of Malassezia restricta Strain KCTC 27527
por: Cho, Yong-Joon, et al.
Publicado: (2019)

Malassezia restricta promotes alcohol-induced liver injury
por: Zeng, Suling, et al.
Publicado: (2023)

Malassezia restricta-mediated Lipoperoxidation: A Novel Trigger in Dandruff
por: JOURDAIN, Roland, et al.
Publicado: (2023)

Genomic Multiplication and Drug Efflux Influence Ketoconazole Resistance in Malassezia restricta
por: Park, Minji, et al.
Publicado: (2020)

Biochemical Properties and Structure Analysis of a DAG-Like Lipase from Malassezia globosa
por: Xu, Huan, et al.
Publicado: (2015)

Understanding the Mechanism of Action of the Anti-Dandruff Agent Zinc Pyrithione against Malassezia restricta
por: Park, Minji, et al.
Publicado: (2018)

Antifungal Mechanism of Action of Lauryl Betaine Against Skin-Associated Fungus Malassezia restricta
por: Do, Eunsoo, et al.
Publicado: (2019)

Activation studies of the β-carbonic anhydrases from Malassezia restricta with amines and amino acids
por: Angeli, Andrea, et al.
Publicado: (2020)

Malassezia restricta Pneumonia in Solid Organ Transplant Recipients: First Report of Two Cases
por: Mularoni, Alessandra, et al.
Publicado: (2021)

Transcriptional Interplay between Malassezia restricta and Staphylococcus Species Co-Existing in the Skin Environment
por: Yang, Hyun Oh, et al.
Publicado: (2023)

The Lid Domain in Lipases: Structural and Functional Determinant of Enzymatic Properties
por: Khan, Faez Iqbal, et al.
Publicado: (2017)

Residue Asn277 Affects the Stability and Substrate Specificity of the SMG1 Lipase from Malassezia globosa
por: Lan, Dongming, et al.
Publicado: (2015)

Complete Genome Sequence of Malassezia restricta CBS 7877, an Opportunist Pathogen Involved in Dandruff and Seborrheic Dermatitis
por: Morand, Stanislas C., et al.
Publicado: (2019)

Sulfonamide Inhibition Profile of the β-Carbonic Anhydrase from Malassezia restricta, An Opportunistic Pathogen Triggering Scalp Conditions
por: Del Prete, Sonia, et al.
Publicado: (2020)

Cloning, Purification, and Characterization of a β-Carbonic Anhydrase from Malassezia restricta, an Opportunistic Pathogen Involved in Dandruff and Seborrheic Dermatitis
por: Del Prete, Sonia, et al.
Publicado: (2019)

Anion Inhibition Profile of the β-Carbonic Anhydrase from the Opportunist Pathogenic Fungus Malassezia restricta Involved in Dandruff and Seborrheic Dermatitis
por: Prete, Sonia Del, et al.
Publicado: (2019)

Skin Commensal Fungus Malassezia and Its Lipases
por: Park, Minji, et al.
Publicado: (2021)

Identification of Phytoconstituents as Potent Inhibitors of Casein Kinase-1 Alpha Using Virtual Screening and Molecular Dynamics Simulations
por: Shafie, Alaa, et al.
Publicado: (2021)

High-throughput virtual screening with e-pharmacophore and molecular simulations study in the designing of pancreatic lipase inhibitors
por: Veeramachaneni, Ganesh Kumar, et al.
Publicado: (2015)

P351 Genetic recombination between the main human skin commensal fungus, Malassezia restricta, and M. globosa using an Agrobacterium tumefaciens-mediated gene transfer system
por: Cho, Otomi, et al.
Publicado: (2022)

Virtual Screening Approach to Identify High-Affinity Inhibitors of Serum and Glucocorticoid-Regulated Kinase 1 among Bioactive Natural Products: Combined Molecular Docking and Simulation Studies
por: Mohammad, Taj, et al.
Publicado: (2020)

Engineering the Thermostability of the Mono- and Diacylglycerol Lipase SMG1 for the Synthesis of Diacylglycerols
por: Li, Lilang, et al.
Publicado: (2022)

Sequence Analysis of Hypothetical Proteins from Helicobacter pylori 26695 to Identify Potential Virulence Factors
por: Naqvi, Ahmad Abu Turab, et al.
Publicado: (2016)

Genome Sequence of the Type Strain Azospira restricta SUA2 (DSM 18626)
por: Mikes, Madison C., et al.
Publicado: (2021)

Optimal Production and Biochemical Properties of a Lipase from Candida albicans
por: Lan, Dongming, et al.
Publicado: (2011)

Integrated virtual screening, molecular modeling and machine learning approaches revealed potential natural inhibitors for epilepsy
por: Alshehri, Faez Falah
Publicado: (2023)

Comparison between Malassezia Folliculitis and Non-Malassezia Folliculitis
por: Song, Hyo Sang, et al.
Publicado: (2014)

A Thermolabile Phospholipase B from Talaromyces marneffei GD-0079: Biochemical Characterization and Structure Dynamics Study
por: Durrani, Rabia, et al.
Publicado: (2020)

Shape based virtual screening and molecular docking towards designing novel pancreatic lipase inhibitors
por: Veeramachaneni, Ganesh Kumar, et al.
Publicado: (2015)

Discovery of Monoacylglycerol Lipase (MAGL) Inhibitors Based on a Pharmacophore-Guided Virtual Screening Study
por: Jha, Vibhu, et al.
Publicado: (2020)

Differential Gene Expression and Weighted Correlation Network Dynamics in High-Throughput Datasets of Prostate Cancer
por: Mohammad, Taj, et al.
Publicado: (2022)

Biochemical Properties of a New Cold-Active Mono- and Diacylglycerol Lipase from Marine Member Janibacter sp. Strain HTCC2649
por: Yuan, Dongjuan, et al.
Publicado: (2014)

Malassezia—Can it be Ignored?
por: Thayikkannu, Ambujavalli Balakrishnan, et al.
Publicado: (2015)

Malassezia and Parkinson's Disease
por: Laurence, Martin, et al.
Publicado: (2019)

A Thermostable Monoacylglycerol Lipase from Marine Geobacillus sp. 12AMOR1: Biochemical Characterization and Mutagenesis Study
por: Tang, Wei, et al.
Publicado: (2019)

Anti-Malassezia Drug Candidates Based on Virulence Factors of Malassezia-Associated Diseases
por: Billamboz, Muriel, et al.
Publicado: (2023)

Target-Based Virtual Screening of Natural Compounds Identifies a Potent Antimalarial With Selective Falcipain-2 Inhibitory Activity
por: Uddin, Amad, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_gb3vardki2ab6rmuff3l2vbooa