Site-Specific Cleavage of RNAs Derived from the PIM1 3′-UTR by a Metal-Free Artificial Ribonuclease

Oligonucleotide conjugates of tris(2-aminobenzimidazole) have been reported previously to cleave complementary RNA strands with high levels of sequence and site specificity. The RNA substrates used in these studies were oligonucleotides not longer than 29-mers. Here we show that ~150–400-mer model t...

Descripción completa

Detalles Bibliográficos
Autores principales: Zellmann, Felix, Thomas, Laura, Scheffer, Ute, Hartmann, Roland K., Göbel, Michael W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412833/
https://www.ncbi.nlm.nih.gov/pubmed/30813393
http://dx.doi.org/10.3390/molecules24040807

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412833/
https://www.ncbi.nlm.nih.gov/pubmed/30813393
http://dx.doi.org/10.3390/molecules24040807

Ejemplares similares