Endoplasmic Reticulum Stress and Unfolded Protein Response in Breast Cancer: The Balance between Apoptosis and Autophagy and Its Role in Drug Resistance

The unfolded protein response (UPR) is a stress response activated by the accumulation of unfolded or misfolded proteins in the lumen of the endoplasmic reticulum (ER) and its uncontrolled activation is mechanistically responsible for several human pathologies, including metabolic, neurodegenerative...

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Detalles Bibliográficos
Autores principales: Sisinni, Lorenza, Pietrafesa, Michele, Lepore, Silvia, Maddalena, Francesca, Condelli, Valentina, Esposito, Franca, Landriscina, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412864/
https://www.ncbi.nlm.nih.gov/pubmed/30781465
http://dx.doi.org/10.3390/ijms20040857

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412864/
https://www.ncbi.nlm.nih.gov/pubmed/30781465
http://dx.doi.org/10.3390/ijms20040857

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