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Ubiquinol-cytochrome C reductase core protein II promotes tumorigenesis by facilitating p53 degradation
BACKGROUND: Ubiquinol-cytochrome C reductase core protein II (QCR2) is essential for mitochondrial functions, yet, its role in cancer development has remained elusive. METHODS: The expression of QCR2 in cancer patients was assessed by immunohistochemistry. The proliferation of cancer cells was asses...
Autores principales: | Han, Yingyan, Wu, Peng, Wang, Zhi, Zhang, Zeyu, Sun, Shujuan, Liu, Jia, Gong, Song, Gao, Peipei, Iwakuma, Tomoo, Molina-Vila, Miguel Angel, Chen, Benjamin Ping-Chi, Zhang, Yu, Ji, Teng, Mo, Qingqing, Chen, Pingbo, Hu, Junbo, Wang, Shixuan, Zhou, Jianfeng, Lu, Hua, Gao, Qinglei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412871/ https://www.ncbi.nlm.nih.gov/pubmed/30674441 http://dx.doi.org/10.1016/j.ebiom.2019.01.002 |
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