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Flavopereirine—An Alkaloid Derived from Geissospermum vellosii—Presents Leishmanicidal Activity In Vitro

Chemotherapy is limited in the treatment of leishmaniasis due to the toxic effects of drugs, low efficacy of alternative treatments, and resistance of the parasite. This work assesses the in vitro activity of flavopereirine on promastigote cultures of Leishmania amazonensis. In addition, an in silic...

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Detalles Bibliográficos
Autores principales: da Silva e Silva, João Victor, Cordovil Brigido, Helliton Patrick, Oliveira de Albuquerque, Kelly Cristina, Miranda Carvalho, Josiwander, Ferreira Reis, Jordano, Vinhal Faria, Lara, Coelho-Ferreira, Márlia Regina, Silveira, Fernando Tobias, da Silva Carneiro, Agnaldo, Percário, Sandro, do Rosário Marinho, Andrey Moacir, Dolabela, Maria Fâni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412932/
https://www.ncbi.nlm.nih.gov/pubmed/30795632
http://dx.doi.org/10.3390/molecules24040785