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Developmental Impairments in a Rat Model of Methyl Donor Deficiency: Effects of a Late Maternal Supplementation with Folic Acid
Vitamins B9 (folate) and B12 act as methyl donors in the one-carbon metabolism which influences epigenetic mechanisms. We previously showed that an embryofetal deficiency of vitamins B9 and B12 in the rat increased brain expression of let-7a and miR-34a microRNAs involved in the developmental contro...
Autores principales: | Geoffroy, Andréa, Saber-Cherif, Lynda, Pourié, Grégory, Helle, Déborah, Umoret, Rémy, Guéant, Jean-Louis, Bossenmeyer-Pourié, Carine, Daval, Jean-Luc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413039/ https://www.ncbi.nlm.nih.gov/pubmed/30813413 http://dx.doi.org/10.3390/ijms20040973 |
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