Cargando…

Roles of MicroRNA-34a in Epithelial to Mesenchymal Transition, Competing Endogenous RNA Sponging and Its Therapeutic Potential

MicroRNA-34a (miR-34a), a tumor suppressor, has been reported to be dysregulated in various human cancers. MiR-34a is involves in certain epithelial-mesenchymal transition (EMT)-associated signal pathways to repress tumorigenesis, cancer progression, and metastasis. Due to the particularity of miR-3...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nie, Dongsong, Fu, Jiewen, Chen, Hanchun, Cheng, Jingliang, Fu, Junjiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413055/ https://www.ncbi.nlm.nih.gov/pubmed/30781524 http://dx.doi.org/10.3390/ijms20040861

Ejemplares similares

MicroRNA-34a targets epithelial to mesenchymal transition-inducing transcription factors (EMT-TFs) and inhibits breast cancer cell migration and invasion
por: Imani, Saber, et al.
Publicado: (2017)

Competing Endogenous RNA Networks in the Epithelial to Mesenchymal Transition in Diffuse-Type of Gastric Cancer
por: Landeros, Natalia, et al.
Publicado: (2020)

Thymoquinone Inhibits the Migration and Invasive Characteristics of Cervical Cancer Cells SiHa and CaSki In Vitro by Targeting Epithelial to Mesenchymal Transition Associated Transcription Factors Twist1 and Zeb1
por: Li, Jun, et al.
Publicado: (2017)

A novel missense variant c.G644A (p.G215E) of the RPGR gene in a Chinese family causes X-linked retinitis pigmentosa
por: Fu, Jiewen, et al.
Publicado: (2019)

Genetic Polymorphism Analysis of 24 Y-STRs in a Han Chinese Population in Luzhou, Southwest China
por: Fu, Jiewen, et al.
Publicado: (2023)

MicroRNA-34 family in breast cancer: from research to therapeutic potential
por: Imani, Saber, et al.
Publicado: (2018)

Prostate adenocarcinoma and COVID‐19: The possible impacts of TMPRSS2 expressions in susceptibility to SARS‐CoV‐2
por: Cheng, Jingliang, et al.
Publicado: (2021)

MicroRNA-34 Family in Cancers: Role, Mechanism, and Therapeutic Potential
por: Fu, Junjiang, et al.
Publicado: (2023)

MicroRNA Regulation of Epithelial to Mesenchymal Transition
por: Abba, Mohammed L., et al.
Publicado: (2016)

Effect of DPP4/CD26 expression on SARS-CoV-2 susceptibility, immune response, adenosine (derivatives m(6)(2)A and CD) regulations on patients with cancer and healthy individuals
por: Du, Jiaman, et al.
Publicado: (2023)

Thymoquinone inhibits cancer metastasis by downregulating TWIST1 expression to reduce epithelial to mesenchymal transition
por: Khan, Md. Asaduzzaman, et al.
Publicado: (2015)

The lncRNA H19 promotes epithelial to mesenchymal transition by functioning as miRNA sponges in colorectal cancer
por: Liang, Wei-Cheng, et al.
Publicado: (2015)

The diagnostic role of microRNA-34a in breast cancer: a systematic review and meta-analysis
por: Imani, Saber, et al.
Publicado: (2017)

Long Noncoding RNA MALAT1 Acts as a Competing Endogenous RNA to Regulate TGF-β2 Induced Epithelial-Mesenchymal Transition of Lens Epithelial Cells by a MicroRNA-26a-Dependent Mechanism
por: Dong, Ning
Publicado: (2019)

DICER-AS1 functions as competing endogenous RNA that targets CSR1 by sponging microRNA-650 and suppresses gastric cancer progression
por: An, Junyan, et al.
Publicado: (2021)

Identification of a novel germline BRCA2 variant in a Chinese breast cancer family
por: Cheng, Jingliang, et al.
Publicado: (2019)

c-Myc Acts as a Competing Endogenous RNA to Sponge miR-34a, in the Upregulation of CD44, in Urothelial Carcinoma
por: Chen, Pie-Che, et al.
Publicado: (2019)

Long noncoding RNA NORAD, a novel competing endogenous RNA, enhances the hypoxia-induced epithelial-mesenchymal transition to promote metastasis in pancreatic cancer
por: Li, Hongzhe, et al.
Publicado: (2017)

The microRNA-200 Family Regulates Epithelial to Mesenchymal Transition
por: Paterson, Emily L., et al.
Publicado: (2008)

MicroRNA Interrelated Epithelial Mesenchymal Transition (EMT) in Glioblastoma
por: Setlai, Botle Precious, et al.
Publicado: (2022)

The Role of MicroRNA in the Regulation of Tumor Epithelial–Mesenchymal Transition
por: Feng, Jing, et al.
Publicado: (2022)

Interferon-alpha competing endogenous RNA network antagonizes microRNA-1270
por: Kimura, Tominori, et al.
Publicado: (2015)

COVID-19 disease and malignant cancers: The impact for the furin gene expression in susceptibility to SARS-CoV-2
por: Li, Dabing, et al.
Publicado: (2021)

Role of microRNA in epithelial to mesenchymal transition and metastasis and clinical perspectives
por: Díaz-López, Antonio, et al.
Publicado: (2014)

MicroRNA of Epithelial to Mesenchymal Transition in Fuchs’ Endothelial Corneal Dystrophy
por: Stunf Pukl, Spela
Publicado: (2022)

Generation of MicroRNA-34 Sponges and Tough Decoys for the Heart: Developments and Challenges
por: Bernardo, Bianca C., et al.
Publicado: (2018)

microRNA Crosstalk Influences Epithelial-to-Mesenchymal, Endothelial-to-Mesenchymal, and Macrophage-to-Mesenchymal Transitions in the Kidney
por: Srivastava, Swayam Prakash, et al.
Publicado: (2019)

A case of Usher syndrome type IIA caused by a rare USH2A homozygous frameshift variant with maternal uniparental disomy (UPD) in a Chinese family
por: Fu, Jiewen, et al.
Publicado: (2020)

Competing endogenous RNA database
por: Sarver, Aaron L, et al.
Publicado: (2012)

Erratum: microRNA Crosstalk Influences Epithelial-to-Mesenchymal, Endothelial-to-Mesenchymal, and Macrophage-to-Mesenchymal Transitions in the Kidney
Publicado: (2020)

MicroRNA-93 Promotes Epithelial–Mesenchymal Transition of Endometrial Carcinoma Cells
por: Chen, Shuo, et al.
Publicado: (2016)

MicroRNA-140 Inhibits the Epithelial-Mesenchymal Transition and Metastasis in Colorectal Cancer
por: Li, Jiazhi, et al.
Publicado: (2018)

Role of microRNA/Epithelial-to-Mesenchymal Transition Axis in the Metastasis of Bladder Cancer
por: Ashrafizadeh, Milad, et al.
Publicado: (2020)

MicroRNA-4287 is a novel tumor suppressor microRNA controlling epithelial-to mesenchymal transition in prostate cancer
por: Bhagirath, Divya, et al.
Publicado: (2020)

Metastatic EMT Phenotype Is Governed by MicroRNA-200-Mediated Competing Endogenous RNA Networks
por: Uhan, Sara, et al.
Publicado: (2021)

Circular RNA PVT1 promotes the invasion and epithelial–mesenchymal transition of breast cancer cells through serving as a competing endogenous RNA for miR-204-5p
por: Bian, Qingzhao
Publicado: (2019)

Circular RNA-Associated Competing Endogenous RNA Network and Prognostic Nomogram for Patients With Colorectal Cancer
por: Song, Wei, et al.
Publicado: (2019)

Genetic polymorphism of 19 autosomal STR loci in the Yi ethnic minority of Liangshan Yi autonomous prefecture from Sichuan province in China
por: Cheng, Jingliang, et al.
Publicado: (2021)

Genetic Polymorphism and Population Genetic Structure Analysis of 21 Autosomal STR Loci for a Han-Chinese Population from Luzhou of Southwest China
por: Song, Binghui, et al.
Publicado: (2023)

LncRNA FOXD2-AS1 Functions as a Competing Endogenous RNA to Regulate TERT Expression by Sponging miR-7-5p in Thyroid Cancer
por: Liu, Xiaoli, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_oog7gccb57j4qvcdsks2frlecn