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MRN (MRE11-RAD50-NBS1) Complex in Human Cancer and Prognostic Implications in Colorectal Cancer

The MRE11-RAD50-NBS1 (MRN) complex has been studied in multiple cancers. The identification of MRN complex mutations in mismatch repair (MMR)-defective cancers has sparked interest in its role in colorectal cancer (CRC). To date, there is evidence indicating a relationship of MRN expression with red...

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Detalles Bibliográficos
Autores principales:	Situ, Yiling, Chung, Liping, Lee, Cheok Soon, Ho, Vincent
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413120/ https://www.ncbi.nlm.nih.gov/pubmed/30769804 http://dx.doi.org/10.3390/ijms20040816

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