Cargando…

Platinum(II) O,S Complexes Inhibit the Aggregation of Amyloid Model Systems

Platinum(II) complexes with different cinnamic acid derivatives as ligands were investigated for their ability to inhibit the aggregation process of amyloid systems derived from Aβ, Yeast Prion Protein Sup35p and the C-terminal domain of nucleophosmin 1. Thioflavin T binding assays and circular dich...

Descripción completa

Detalles Bibliográficos
Autores principales:	Florio, Daniele, Malfitano, Anna Maria, Di Somma, Sarah, Mügge, Carolin, Weigand, Wolfgang, Ferraro, Giarita, Iacobucci, Ilaria, Monti, Maria, Morelli, Giancarlo, Merlino, Antonello, Marasco, Daniela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413125/ https://www.ncbi.nlm.nih.gov/pubmed/30769904 http://dx.doi.org/10.3390/ijms20040829

Ejemplares similares

Role of the Metal Center in the Modulation of the Aggregation Process of Amyloid Model Systems by Square Planar Complexes Bearing 2-(2′-pyridyl)benzimidazole Ligands
por: Florio, Daniele, et al.
Publicado: (2019)

Modulation of Amyloidogenic Peptide Aggregation by Photoactivatable CO-Releasing Ruthenium(II) Complexes
por: Florio, Daniele, et al.
Publicado: (2020)

A Comparative Study of the Effects of Platinum (II) Complexes on β-Amyloid Aggregation: Potential Neurodrug Applications
por: Manna, Sara La, et al.
Publicado: (2021)

Glucosyl Platinum(II) Complexes Inhibit Aggregation of the C-Terminal Region of the Aβ Peptide
por: La Manna, Sara, et al.
Publicado: (2022)

Metal-Complexes Bearing Releasable CO Differently Modulate Amyloid Aggregation
por: La Manna, Sara, et al.
Publicado: (2023)

Reaction with Proteins of a Five-Coordinate Platinum(II) Compound
por: Ferraro, Giarita, et al.
Publicado: (2019)

Protein-Based Delivery Systems for Anticancer Metallodrugs: Structure and Biological Activity of the Oxaliplatin/β-Lactoglobulin Adduct
por: Monti, Daria Maria, et al.
Publicado: (2022)

Metallodrugs: Mechanisms of Action, Molecular Targets and Biological Activity
por: Ferraro, Giarita, et al.
Publicado: (2022)

Reactions with Proteins of Three Novel Anticancer Platinum(II) Complexes Bearing N-Heterocyclic Ligands
por: Sacco, Francesca, et al.
Publicado: (2021)

Unusual Structural Features in the Adduct of Dirhodium Tetraacetate with Lysozyme
por: Loreto, Domenico, et al.
Publicado: (2021)

Arsenoplatin-Ferritin Nanocage: Structure and Cytotoxicity
por: Ferraro, Giarita, et al.
Publicado: (2021)

A new and efficient procedure to load bioactive molecules within the human heavy-chain ferritin nanocage
por: Lucignano, Rosanna, et al.
Publicado: (2023)

Evaluation of Auranofin Loading within Ferritin Nanocages
por: Lucignano, Rosanna, et al.
Publicado: (2022)

Pt(II) versus Pt(IV) in Carbene Glycoconjugate Antitumor Agents: Minimal Structural Variations and Great Performance Changes
por: Annunziata, Alfonso, et al.
Publicado: (2020)

Biotic and environmental stress induces nitration and changes in structure and function of the sea urchin major yolk protein toposome
por: Castellano, Immacolata, et al.
Publicado: (2018)

Multiple and Variable Binding of Pharmacologically Active Bis(maltolato)oxidovanadium(IV) to Lysozyme
por: Ferraro, Giarita, et al.
Publicado: (2022)

Cisplatin Binding to Human Serum Transferrin: A Crystallographic Study
por: Troisi, Romualdo, et al.
Publicado: (2023)

Insights into Network of Hot Spots of Aggregation in Nucleophosmin 1
por: Florio, Daniele, et al.
Publicado: (2022)

Mitochondria Targeting with Luminescent Rhenium(I) Complexes
por: Skiba, Joanna, et al.
Publicado: (2017)

Effect of Equatorial Ligand Substitution on the Reactivity with Proteins of Paddlewheel Diruthenium Complexes: Structural Studies
por: Terán, Aarón, et al.
Publicado: (2023)

Implications of Protein Interaction in the Speciation of Potential V(IV)O–Pyridinone Drugs
por: Ferraro, Giarita, et al.
Publicado: (2023)

Spectroscopic/Computational Characterization and the X-ray Structure of the Adduct of the V(IV)O–Picolinato Complex with RNase A
por: Ferraro, Giarita, et al.
Publicado: (2021)

Impact of Hydrophobic Chains in Five-Coordinate Glucoconjugate Pt(II) Anticancer Agents
por: Annunziata, Alfonso, et al.
Publicado: (2023)

Amyloid-Like Aggregation in Diseases and Biomaterials: Osmosis of Structural Information
por: Balasco, Nicole, et al.
Publicado: (2021)

Plant isoquinoline alkaloids as potential neurodrugs: A comparative study of the effects of benzo[c]phenanthridine and berberine-based compounds on β-amyloid aggregation
por: Marasco, Daniela, et al.
Publicado: (2021)

Inside out Porphyridium cruentum: Beyond the Conventional Biorefinery Concept
por: Liberti, Davide, et al.
Publicado: (2022)

Impact of Amyloid-β on Platelet Mitochondrial Function and Platelet–Mediated Amyloid Aggregation in Alzheimer’s Disease
por: Donner, Lili, et al.
Publicado: (2021)

Amyloids and protein aggregation
por: Linse, Sara, et al.
Publicado: (2023)

Reply to Comment on “Malfitano, A.M. et al. Virotherapy as a Potential Therapeutic Approach for the Treatment of Aggressive Thyroid Cancer” Cancers 2019, 11, 1532
por: Malfitano, Anna Maria, et al.
Publicado: (2020)

Virotherapy as a Potential Therapeutic Approach for the Treatment of Aggressive Thyroid Cancer
por: Malfitano, Anna Maria, et al.
Publicado: (2019)

Cross Talk of Macrophages with Tumor Microenvironment Cells and Modulation of Macrophages in Cancer by Virotherapy
por: Di Somma, Sarah, et al.
Publicado: (2021)

Amyloid Beta Aggregation in the Presence of Temperature-Sensitive Polymers
por: Funtan, Sebastian, et al.
Publicado: (2016)

Misfolding and Amyloid Aggregation of Apomyoglobin
por: Iannuzzi, Clara, et al.
Publicado: (2013)

The yin and yang of amyloid aggregation
por: Falsone, S Fabio
Publicado: (2015)

Structure and Aggregation Mechanisms in Amyloids
por: L. Almeida, Zaida, et al.
Publicado: (2020)

Natural Inhibitors of Amyloid Aggregation
por: Tortora, Paolo, et al.
Publicado: (2023)

Molecular signaling involving intrinsically disordered proteins in prostate cancer
por: Russo, Anna, et al.
Publicado: (2016)

Images from the Haematologica Atlas of Hematologic Cytology: trypanosomiasis
por: Malfitano, Antonello, et al.
Publicado: (2021)

Images from the Haematologica Atlas of Hematologic Cytology: visceral leishmaniasis
por: Invernizzi, Rosangela, et al.
Publicado: (2021)

Images from the Haematologica Atlas of Hematologic Cytology: filariasis
por: Malfitano, Antonello, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_1llt0raiq58bds0ml8kq7lip75