O-glycans truncation modulates gastric cancer cell signaling and transcription leading to a more aggressive phenotype

BACKGROUND: Changes in glycosylation are known to play critical roles during gastric carcinogenesis. Expression of truncated O-glycans, such as the Sialyl-Tn (STn) antigen, is a common feature shared by many cancers and is associated with cancer aggressiveness and poor-prognosis. METHODS: Glycoengin...

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Detalles Bibliográficos
Autores principales: Freitas, Daniela, Campos, Diana, Gomes, Joana, Pinto, Filipe, Macedo, Joana A., Matos, Rita, Mereiter, Stefan, Pinto, Marta T., Polónia, António, Gartner, Fátima, Magalhães, Ana, Reis, Celso A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413340/
https://www.ncbi.nlm.nih.gov/pubmed/30662000
http://dx.doi.org/10.1016/j.ebiom.2019.01.017

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