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Long non-coding RNA CASC2 suppresses pulmonary artery smooth muscle cell proliferation and phenotypic switch in hypoxia-induced pulmonary hypertension

BACKGROUND: In this study, we aimed to investigate whether and how lncRNA CASC2 was involved in hypoxia-induced pulmonary hypertension (PH)-related vascular remodeling. METHODS: The expression of lncRNAs or mRNAs was detected by qRT-PCR, and western blot analysis or immunochemistry was employed for...

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Detalles Bibliográficos
Autores principales: Gong, Junsong, Chen, Zujun, Chen, Yu, Lv, Huanran, Lu, Haisong, Yan, Fuxia, Li, Lihuan, Zhang, Weili, Shi, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413462/
https://www.ncbi.nlm.nih.gov/pubmed/30857524
http://dx.doi.org/10.1186/s12931-019-1018-x

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