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Yoga in Children with Epilepsy: A Randomized Controlled Trial

CONTEXT: Majority of epilepsy begins in childhood. Twenty to thirty percent of patients may not respond to antiepileptic drugs. Yoga as a complementary therapy has been found to be beneficial in adults, but has not yet been studied in children with epilepsy. AIM: To study the effect of yoga on seizu...

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Autores principales: Kanhere, Sujata V., Bagadia, Deepak R., Phadke, Varsha D., Mukherjee, Priyashree S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413605/
https://www.ncbi.nlm.nih.gov/pubmed/30937081
http://dx.doi.org/10.4103/JPN.JPN_88_18
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author Kanhere, Sujata V.
Bagadia, Deepak R.
Phadke, Varsha D.
Mukherjee, Priyashree S.
author_facet Kanhere, Sujata V.
Bagadia, Deepak R.
Phadke, Varsha D.
Mukherjee, Priyashree S.
author_sort Kanhere, Sujata V.
collection PubMed
description CONTEXT: Majority of epilepsy begins in childhood. Twenty to thirty percent of patients may not respond to antiepileptic drugs. Yoga as a complementary therapy has been found to be beneficial in adults, but has not yet been studied in children with epilepsy. AIM: To study the effect of yoga on seizure and electroencephalogram (EEG) outcome in children with epilepsy. SETTING AND DESIGN: A randomized controlled trial was conducted in the pediatric neurology outpatient department of a tertiary care teaching hospital. MATERIALS AND METHODS: Twenty children aged 8–12 years with an unequivocal diagnosis of epilepsy on regular antiepileptic drugs were enrolled. Yoga therapy was provided to 10 children (study group) and 10 children formed the control group. Yoga therapy was given as 10 sessions of 1h each. We compared seizure frequency and EEG at baseline, 3, and 6 months. Statistical analysis was carried out using standard statistical tests. A P value of <0.05 was considered significant. RESULTS: No children had seizures at the end of 3 and 6 months in the study group. In the control group, at 3 and 6 months, four and three children, respectively, had seizures. Eight children each in both the groups had an abnormal EEG at enrollment. At the end of 6 months, one EEG in the study group and seven in the control group were abnormal (P = 0.020). CONCLUSION: Yoga as an additional therapy in children with epilepsy leads to seizure freedom and significant improvement in EEG at 6 months.
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spelling pubmed-64136052019-04-01 Yoga in Children with Epilepsy: A Randomized Controlled Trial Kanhere, Sujata V. Bagadia, Deepak R. Phadke, Varsha D. Mukherjee, Priyashree S. J Pediatr Neurosci Original Article CONTEXT: Majority of epilepsy begins in childhood. Twenty to thirty percent of patients may not respond to antiepileptic drugs. Yoga as a complementary therapy has been found to be beneficial in adults, but has not yet been studied in children with epilepsy. AIM: To study the effect of yoga on seizure and electroencephalogram (EEG) outcome in children with epilepsy. SETTING AND DESIGN: A randomized controlled trial was conducted in the pediatric neurology outpatient department of a tertiary care teaching hospital. MATERIALS AND METHODS: Twenty children aged 8–12 years with an unequivocal diagnosis of epilepsy on regular antiepileptic drugs were enrolled. Yoga therapy was provided to 10 children (study group) and 10 children formed the control group. Yoga therapy was given as 10 sessions of 1h each. We compared seizure frequency and EEG at baseline, 3, and 6 months. Statistical analysis was carried out using standard statistical tests. A P value of <0.05 was considered significant. RESULTS: No children had seizures at the end of 3 and 6 months in the study group. In the control group, at 3 and 6 months, four and three children, respectively, had seizures. Eight children each in both the groups had an abnormal EEG at enrollment. At the end of 6 months, one EEG in the study group and seven in the control group were abnormal (P = 0.020). CONCLUSION: Yoga as an additional therapy in children with epilepsy leads to seizure freedom and significant improvement in EEG at 6 months. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC6413605/ /pubmed/30937081 http://dx.doi.org/10.4103/JPN.JPN_88_18 Text en Copyright: © 2019 Journal of Pediatric Neurosciences http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Kanhere, Sujata V.
Bagadia, Deepak R.
Phadke, Varsha D.
Mukherjee, Priyashree S.
Yoga in Children with Epilepsy: A Randomized Controlled Trial
title Yoga in Children with Epilepsy: A Randomized Controlled Trial
title_full Yoga in Children with Epilepsy: A Randomized Controlled Trial
title_fullStr Yoga in Children with Epilepsy: A Randomized Controlled Trial
title_full_unstemmed Yoga in Children with Epilepsy: A Randomized Controlled Trial
title_short Yoga in Children with Epilepsy: A Randomized Controlled Trial
title_sort yoga in children with epilepsy: a randomized controlled trial
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413605/
https://www.ncbi.nlm.nih.gov/pubmed/30937081
http://dx.doi.org/10.4103/JPN.JPN_88_18
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