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LRH1-driven transcription factor circuitry for hepatocyte identity: Super-enhancer cistromic analysis
BACKGROUND: The injured liver loses normal function, with concomitant decrease of key identity genes. Super-enhancers contribute to mammalian cell identity. Here, we identified core transcription factors (TFs) that are active in hepatocytes, using genome-wide analysis and hierarchical ordering of su...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413675/ https://www.ncbi.nlm.nih.gov/pubmed/30638865 http://dx.doi.org/10.1016/j.ebiom.2018.12.056 |