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Morphine biotransformation genes and neonatal clinical factors predicted behaviour problems in very preterm children at 18 months
BACKGROUND: Behaviour problems are prevalent among children born very preterm (≤ 32 weeks gestation), and have been associated with morphine exposure. Morphine accumulation in the brain is determined by genetic variations related to morphine biotransformation. The objective of the study was to inves...
Autores principales: | Chau, Cecil M.Y., Ross, Colin J.D., Chau, Vann, Synnes, Anne R., Miller, Steven P., Carleton, Bruce, Grunau, Ruth E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413679/ https://www.ncbi.nlm.nih.gov/pubmed/30709768 http://dx.doi.org/10.1016/j.ebiom.2019.01.042 |
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