FoxO3a inhibiting expression of EPS8 to prevent progression of NSCLC: A new negative loop of EGFR signaling

BACKGROUND: The resistance to EGF receptor (EGFR) tyrosine kinase inhibitors (TKI) is a major challenge in the treatment of non-small cell lung cancer (NSCLC). Understanding the molecular mechanisms behind resistance is therefore an important issue. Here we assessed the role of EGFR pathway substrat...

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Detalles Bibliográficos
Autores principales: Wen, Qiang, Jiao, Xinwei, Kuang, Fei, Hou, Beibei, Zhu, Yajing, Guo, Wenyu, Sun, Guangxin, Ba, Yufeng, Yu, Dandan, Wang, David, Zhang, Faya, Qiao, Hui Chao, Wang, Shuolin, Tang, Shu, Qiao, Hailing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413682/
https://www.ncbi.nlm.nih.gov/pubmed/30738830
http://dx.doi.org/10.1016/j.ebiom.2019.01.053

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