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fMRI Reveals Mitigation of Cerebrovascular Dysfunction by Bradykinin Receptors 1 and 2 Inhibitor Noscapine in a Mouse Model of Cerebral Amyloidosis

Functional magnetic resonance imaging (fMRI) techniques can be used to assess cerebrovascular dysfunction in Alzheimer’s disease, an important and early contributor to pathology. We hypothesized that bradykinin receptor inhibition alleviates the vascular dysfunction in a transgenic arcAβ mouse model...

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Detalles Bibliográficos
Autores principales: Ni, Ruiqing, Kindler, Diana Rita, Waag, Rebecca, Rouault, Marie, Ravikumar, Priyanka, Nitsch, Roger, Rudin, Markus, Camici, Giovanni G., Liberale, Luca, Kulic, Luka, Klohs, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413713/
https://www.ncbi.nlm.nih.gov/pubmed/30890928
http://dx.doi.org/10.3389/fnagi.2019.00027

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