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fMRI Reveals Mitigation of Cerebrovascular Dysfunction by Bradykinin Receptors 1 and 2 Inhibitor Noscapine in a Mouse Model of Cerebral Amyloidosis
Functional magnetic resonance imaging (fMRI) techniques can be used to assess cerebrovascular dysfunction in Alzheimer’s disease, an important and early contributor to pathology. We hypothesized that bradykinin receptor inhibition alleviates the vascular dysfunction in a transgenic arcAβ mouse model...
Autores principales: | Ni, Ruiqing, Kindler, Diana Rita, Waag, Rebecca, Rouault, Marie, Ravikumar, Priyanka, Nitsch, Roger, Rudin, Markus, Camici, Giovanni G., Liberale, Luca, Kulic, Luka, Klohs, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413713/ https://www.ncbi.nlm.nih.gov/pubmed/30890928 http://dx.doi.org/10.3389/fnagi.2019.00027 |
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