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Integration of single-cell RNA-seq data into population models to characterize cancer metabolism

Metabolic reprogramming is a general feature of cancer cells. Regrettably, the comprehensive quantification of metabolites in biological specimens does not promptly translate into knowledge on the utilization of metabolic pathways. By estimating fluxes across metabolic pathways, computational models...

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Detalles Bibliográficos
Autores principales:	Damiani, Chiara, Maspero, Davide, Di Filippo, Marzia, Colombo, Riccardo, Pescini, Dario, Graudenzi, Alex, Westerhoff, Hans Victor, Alberghina, Lilia, Vanoni, Marco, Mauri, Giancarlo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413955/ https://www.ncbi.nlm.nih.gov/pubmed/30818329 http://dx.doi.org/10.1371/journal.pcbi.1006733

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