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Berberine prevents human nucleus pulposus cells from IL-1β-induced extracellular matrix degradation and apoptosis by inhibiting the NF-κB pathway
Intervertebral disc degeneration (IDD) is widely considered to be one of the main causes of lower back pain, which is a chronic progressive disease closely related to inflammation, nucleus pulposus (NP) cell apoptosis and extracellular matrix (ECM) degradation. Berberine (BBR) is an alkaloid compoun...
Autores principales: | Lu, Lin, Hu, Jialang, Wu, Qipeng, An, Ying, Cui, Wei, Wang, Junwen, Ye, Zhewei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414164/ https://www.ncbi.nlm.nih.gov/pubmed/30816449 http://dx.doi.org/10.3892/ijmm.2019.4105 |
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