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Metformin prevents nephrolithiasis formation by inhibiting the expression of OPN and MCP-1 in vitro and in vivo

Treatment targeting osteopontin (OPN) and monocyte chemoattractant protein 1 (MCP-1) has been recognized as a novel approach in renal crystal formation. The present study was designed to investigate the suppressive effects of metformin on nephrolithiasis formation and its potential mechanism. The cy...

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Detalles Bibliográficos
Autores principales:	Yang, Xiong, Yang, Tong, Li, Jie, Yang, Rui, Qi, Shiyong, Zhao, Yang, Li, Liang, Li, Jingjin, Zhang, Xuening, Yang, Kuo, Xu, Yong, Liu, Chunyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414169/ https://www.ncbi.nlm.nih.gov/pubmed/30720053 http://dx.doi.org/10.3892/ijmm.2019.4084

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