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Pre-attentive Mismatch Response and Involuntary Attention Switching to a Deviance in an Earlier-Than-Usual Auditory Stimulus: An ERP Study

An acoustic stimulus elicits an electroencephalographic response called auditory event-related potential (ERP). When some members of a stream of standard auditory stimuli are replaced randomly by a deviant stimulus and this stream is presented to a subject who ignores the stimuli, two different ERPs...

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Autores principales: Ungan, Pekcan, Karsilar, Hakan, Yagcioglu, Suha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414453/
https://www.ncbi.nlm.nih.gov/pubmed/30894807
http://dx.doi.org/10.3389/fnhum.2019.00058
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author Ungan, Pekcan
Karsilar, Hakan
Yagcioglu, Suha
author_facet Ungan, Pekcan
Karsilar, Hakan
Yagcioglu, Suha
author_sort Ungan, Pekcan
collection PubMed
description An acoustic stimulus elicits an electroencephalographic response called auditory event-related potential (ERP). When some members of a stream of standard auditory stimuli are replaced randomly by a deviant stimulus and this stream is presented to a subject who ignores the stimuli, two different ERPs to deviant and standard stimuli are recorded. If the ERP to standard stimuli is subtracted from the ERP to deviant stimuli, the difference potential (DP) waveform typically exhibits a series of negative-positive-negative deflections called mismatch negativity (MMN), P3a, and reorienting negativity (RON), which are associated with pre-attentive change detection, involuntary attention switching, and reorienting of attention, respectively. The aim of the present study was to investigate how these pre-attentive processes are affected if the change occurs earlier than its usual timing implied by isochronous standard stimuli. In the MMN paradigm employed, 15% of the standards were randomly replaced by deviant stimuli which differed either in their pitch, their earlier onset time, or in both. Event-related responses to these three deviants [timely pitch change (R(TP)), earlier onset (R(EO)), earlier pitch change (R(EP))] and to standards (R(S)) were recorded from 10 reading subjects. To maintain identical stimulation histories for the responses subtracted from each other, “deviant-standard” difference potentials (DP) for “timely” and “early” pitch deviances were derived as follows: DP(TP) = R(TP) − R(S) and DP(EP) = R(EP) − R(EO). Interestingly, the MMN components of the DPs to timely and early pitch deviances had similar amplitudes, indicating that regularity of stimulus timing does not provide any benefit for the pre-attentive auditory change detection mechanism. However, different scalp current density (SCD) dynamics of the MMN/P3a complexes, elicited by timely and early pitch deviances, suggested that an auditory change in a stimulus occurring earlier-than-usual initiates a faster and more effective call-for-attention and causes stronger attention switching than a timely change. SCD results also indicated that the temporal, frontal, and parietal MMN components are simultaneously present rather than emerging sequentially in time, supporting the MMN models based on parallel deviance processing in the respective cortices. Similarity of the RONs to timely and early pitch deviances indicated that reorienting of attention is of the same strength in two cases.
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spelling pubmed-64144532019-03-20 Pre-attentive Mismatch Response and Involuntary Attention Switching to a Deviance in an Earlier-Than-Usual Auditory Stimulus: An ERP Study Ungan, Pekcan Karsilar, Hakan Yagcioglu, Suha Front Hum Neurosci Neuroscience An acoustic stimulus elicits an electroencephalographic response called auditory event-related potential (ERP). When some members of a stream of standard auditory stimuli are replaced randomly by a deviant stimulus and this stream is presented to a subject who ignores the stimuli, two different ERPs to deviant and standard stimuli are recorded. If the ERP to standard stimuli is subtracted from the ERP to deviant stimuli, the difference potential (DP) waveform typically exhibits a series of negative-positive-negative deflections called mismatch negativity (MMN), P3a, and reorienting negativity (RON), which are associated with pre-attentive change detection, involuntary attention switching, and reorienting of attention, respectively. The aim of the present study was to investigate how these pre-attentive processes are affected if the change occurs earlier than its usual timing implied by isochronous standard stimuli. In the MMN paradigm employed, 15% of the standards were randomly replaced by deviant stimuli which differed either in their pitch, their earlier onset time, or in both. Event-related responses to these three deviants [timely pitch change (R(TP)), earlier onset (R(EO)), earlier pitch change (R(EP))] and to standards (R(S)) were recorded from 10 reading subjects. To maintain identical stimulation histories for the responses subtracted from each other, “deviant-standard” difference potentials (DP) for “timely” and “early” pitch deviances were derived as follows: DP(TP) = R(TP) − R(S) and DP(EP) = R(EP) − R(EO). Interestingly, the MMN components of the DPs to timely and early pitch deviances had similar amplitudes, indicating that regularity of stimulus timing does not provide any benefit for the pre-attentive auditory change detection mechanism. However, different scalp current density (SCD) dynamics of the MMN/P3a complexes, elicited by timely and early pitch deviances, suggested that an auditory change in a stimulus occurring earlier-than-usual initiates a faster and more effective call-for-attention and causes stronger attention switching than a timely change. SCD results also indicated that the temporal, frontal, and parietal MMN components are simultaneously present rather than emerging sequentially in time, supporting the MMN models based on parallel deviance processing in the respective cortices. Similarity of the RONs to timely and early pitch deviances indicated that reorienting of attention is of the same strength in two cases. Frontiers Media S.A. 2019-03-06 /pmc/articles/PMC6414453/ /pubmed/30894807 http://dx.doi.org/10.3389/fnhum.2019.00058 Text en Copyright © 2019 Ungan, Karsilar and Yagcioglu. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Ungan, Pekcan
Karsilar, Hakan
Yagcioglu, Suha
Pre-attentive Mismatch Response and Involuntary Attention Switching to a Deviance in an Earlier-Than-Usual Auditory Stimulus: An ERP Study
title Pre-attentive Mismatch Response and Involuntary Attention Switching to a Deviance in an Earlier-Than-Usual Auditory Stimulus: An ERP Study
title_full Pre-attentive Mismatch Response and Involuntary Attention Switching to a Deviance in an Earlier-Than-Usual Auditory Stimulus: An ERP Study
title_fullStr Pre-attentive Mismatch Response and Involuntary Attention Switching to a Deviance in an Earlier-Than-Usual Auditory Stimulus: An ERP Study
title_full_unstemmed Pre-attentive Mismatch Response and Involuntary Attention Switching to a Deviance in an Earlier-Than-Usual Auditory Stimulus: An ERP Study
title_short Pre-attentive Mismatch Response and Involuntary Attention Switching to a Deviance in an Earlier-Than-Usual Auditory Stimulus: An ERP Study
title_sort pre-attentive mismatch response and involuntary attention switching to a deviance in an earlier-than-usual auditory stimulus: an erp study
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414453/
https://www.ncbi.nlm.nih.gov/pubmed/30894807
http://dx.doi.org/10.3389/fnhum.2019.00058
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