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Polygenic risk and hazard scores for Alzheimer's disease prediction

OBJECTIVE: Genome‐wide association studies (GWAS) have identified over 30 susceptibility loci associated with Alzheimer's disease (AD). Using AD GWAS data from the International Genomics of Alzheimer's Project (IGAP), Polygenic Risk Score (PRS) was successfully applied to predict life time...

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Detalles Bibliográficos
Autores principales:	Leonenko, Ganna, Sims, Rebecca, Shoai, Maryam, Frizzati, Aura, Bossù, Paola, Spalletta, Gianfranco, Fox, Nick C., Williams, Julie, Hardy, John, Escott‐Price, Valentina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414493/ https://www.ncbi.nlm.nih.gov/pubmed/30911569 http://dx.doi.org/10.1002/acn3.716

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