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Carbon replicas reveal double stranded structure of tight junctions in phase-contrast electron microscopy
Replica-based freeze-fracture and freeze-etching electron microscopy methods provide surface topography information, particularly suited to studying membrane protein complexes in their native context. The fidelity and resolution of metal replicas is limited by the inherent property of metal atoms to...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414538/ https://www.ncbi.nlm.nih.gov/pubmed/30886907 http://dx.doi.org/10.1038/s42003-019-0319-4 |