Wnt/β-catenin signaling, which is activated in odontomas, reduces Sema3A expression to regulate odontogenic epithelial cell proliferation and tooth germ development

Odontomas, developmental anomalies of tooth germ, frequently occur in familial adenomatous polyposis patients with activated Wnt/β-catenin signaling. However, roles of Wnt/β-catenin signaling in odontomas or odontogenic cells are unclear. Herein, we investigated β-catenin expression in odontomas and...

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Detalles Bibliográficos
Autores principales: Fujii, Shinsuke, Nagata, Kengo, Matsumoto, Shinji, Kohashi, Ken-ichi, Kikuchi, Akira, Oda, Yoshinao, Kiyoshima, Tamotsu, Wada, Naohisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414619/
https://www.ncbi.nlm.nih.gov/pubmed/30862786
http://dx.doi.org/10.1038/s41598-019-39686-1

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