Investigating spontaneous retinal venous pulsation using Doppler optical coherence tomography

We demonstrate the advantages of optical coherence tomography (OCT) imaging for investigation of spontaneous retinal venous pulsation (SRVP). The pulsatile changes in venous vessel caliber are analyzed qualitatively and quantitatively using conventional intensity-based OCT as well as the functional...

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Autores principales: Wartak, Andreas, Beer, Florian, Desissaire, Sylvia, Baumann, Bernhard, Pircher, Michael, Hitzenberger, Christoph K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414623/
https://www.ncbi.nlm.nih.gov/pubmed/30862956
http://dx.doi.org/10.1038/s41598-019-40961-4
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author Wartak, Andreas
Beer, Florian
Desissaire, Sylvia
Baumann, Bernhard
Pircher, Michael
Hitzenberger, Christoph K.
author_facet Wartak, Andreas
Beer, Florian
Desissaire, Sylvia
Baumann, Bernhard
Pircher, Michael
Hitzenberger, Christoph K.
author_sort Wartak, Andreas
collection PubMed
description We demonstrate the advantages of optical coherence tomography (OCT) imaging for investigation of spontaneous retinal venous pulsation (SRVP). The pulsatile changes in venous vessel caliber are analyzed qualitatively and quantitatively using conventional intensity-based OCT as well as the functional extension Doppler OCT (DOCT). Single-channel and double-channel line scanning protocols of our multi-channel OCT prototype are employed to investigate venous pulsatile caliber oscillations as well as venous flow pulsatility in the eyes of healthy volunteers. A comparison to recordings of scanning laser ophthalmoscopy (SLO) – a standard en-face imaging modality for evaluation of SRVP – is provided, emphasizing the advantages of tomographic image acquisition. To the best of our knowledge, this is the first quantitative time-resolved investigation of SRVP and associated retinal perfusion characteristics using OCT.
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spelling pubmed-64146232019-03-14 Investigating spontaneous retinal venous pulsation using Doppler optical coherence tomography Wartak, Andreas Beer, Florian Desissaire, Sylvia Baumann, Bernhard Pircher, Michael Hitzenberger, Christoph K. Sci Rep Article We demonstrate the advantages of optical coherence tomography (OCT) imaging for investigation of spontaneous retinal venous pulsation (SRVP). The pulsatile changes in venous vessel caliber are analyzed qualitatively and quantitatively using conventional intensity-based OCT as well as the functional extension Doppler OCT (DOCT). Single-channel and double-channel line scanning protocols of our multi-channel OCT prototype are employed to investigate venous pulsatile caliber oscillations as well as venous flow pulsatility in the eyes of healthy volunteers. A comparison to recordings of scanning laser ophthalmoscopy (SLO) – a standard en-face imaging modality for evaluation of SRVP – is provided, emphasizing the advantages of tomographic image acquisition. To the best of our knowledge, this is the first quantitative time-resolved investigation of SRVP and associated retinal perfusion characteristics using OCT. Nature Publishing Group UK 2019-03-12 /pmc/articles/PMC6414623/ /pubmed/30862956 http://dx.doi.org/10.1038/s41598-019-40961-4 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Wartak, Andreas
Beer, Florian
Desissaire, Sylvia
Baumann, Bernhard
Pircher, Michael
Hitzenberger, Christoph K.
Investigating spontaneous retinal venous pulsation using Doppler optical coherence tomography
title Investigating spontaneous retinal venous pulsation using Doppler optical coherence tomography
title_full Investigating spontaneous retinal venous pulsation using Doppler optical coherence tomography
title_fullStr Investigating spontaneous retinal venous pulsation using Doppler optical coherence tomography
title_full_unstemmed Investigating spontaneous retinal venous pulsation using Doppler optical coherence tomography
title_short Investigating spontaneous retinal venous pulsation using Doppler optical coherence tomography
title_sort investigating spontaneous retinal venous pulsation using doppler optical coherence tomography
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414623/
https://www.ncbi.nlm.nih.gov/pubmed/30862956
http://dx.doi.org/10.1038/s41598-019-40961-4
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