Cargando…
Primary lung cancer samples cultured under microenvironment-mimetic conditions enrich for mesenchymal stem-like cells that promote metastasis
The tumor microenvironment (TME) is composed of a heterogeneous biological ecosystem of cellular and non-cellular elements including transformed tumor cells, endothelial cells, immune cells, activated fibroblasts or myofibroblasts, stem and progenitor cells, as well as the cytokines and matrix that...
Autores principales: | Saforo, Douglas, Omer, Linda, Smolenkov, Andrei, Barve, Aditya, Casson, Lavona, Boyd, Nolan, Clark, Geoffrey, Siskind, Leah, Beverly, Levi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414636/ https://www.ncbi.nlm.nih.gov/pubmed/30862796 http://dx.doi.org/10.1038/s41598-019-40519-4 |
Ejemplares similares
-
Perturbation of Methionine/S-adenosylmethionine Metabolism as a Novel Vulnerability in MLL Rearranged Leukemia
por: Barve, Aditya, et al.
Publicado: (2019) -
Inhibition of Ceramide Metabolism Sensitizes Human Leukemia Cells to Inhibition of BCL2-Like Proteins
por: Casson, Lavona, et al.
Publicado: (2013) -
Computational/experimental evaluation of liver metastasis post hepatic injury: interactions with macrophages and transitional ECM
por: Hudson, Shanice V., et al.
Publicado: (2019) -
Towards a molecular understanding of the overlapping and distinct roles of UBQLN1 and UBQLN2 in lung cancer progression and metastasis
por: Shah, Parag P., et al.
Publicado: (2022) -
Common cytotoxic chemotherapeutics induce epithelial-mesenchymal transition (EMT) downstream of ER stress
por: Shah, Parag P., et al.
Publicado: (2017)