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A small molecule Nec-1 directly induces amyloid clearance in the brains of aged APP/PS1 mice

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by the formation of toxic amyloid-β (Aβ) oligomers and plaques. Considering that Aβ misfolding and aggregation precedes the progressive development of cognitive impairment in AD, investigating a therapeutic means by c...

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Detalles Bibliográficos
Autores principales:	Yang, Seung-Hoon, Shin, Jisu, Shin, Naewoo Neo, Hwang, Ji-Hyun, Hong, Sung-Chul, Park, Keunwan, Lee, Jae Wook, Lee, Sejin, Baek, Seungyeop, Kim, Kyeonghwan, Cho, Illhwan, Kim, YoungSoo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414664/ https://www.ncbi.nlm.nih.gov/pubmed/30862818 http://dx.doi.org/10.1038/s41598-019-40205-5

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