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Label-free detection of conformational changes in switchable DNA nanostructures with microwave microfluidics

Detection of conformational changes in biomolecular assemblies provides critical information into biological and self-assembly processes. State-of-the-art in situ biomolecular conformation detection techniques rely on fluorescent labels or protein-specific binding agents to signal conformational cha...

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Detalles Bibliográficos
Autores principales: Stelson, Angela C., Liu, Minghui, Little, Charles A. E., Long, Christian J., Orloff, Nathan D., Stephanopoulos, Nicholas, Booth, James C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414672/
https://www.ncbi.nlm.nih.gov/pubmed/30862776
http://dx.doi.org/10.1038/s41467-019-09017-z