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Serum Amyloid P Component Binds Fungal Surface Amyloid and Decreases Human Macrophage Phagocytosis and Secretion of Inflammatory Cytokines
In patients with invasive fungal diseases, there is often little cellular inflammatory response. We tested the idea that binding of the human constitutive plasma protein serum amyloid P component (SAP) (also called PTX2) to Candida albicans dampens the innate immune response to this fungus. Many pat...
Autores principales: | Behrens, Nicole E., Lipke, Peter N., Pilling, Darrell, Gomer, Richard H., Klotz, Stephen A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414697/ https://www.ncbi.nlm.nih.gov/pubmed/30862745 http://dx.doi.org/10.1128/mBio.00218-19 |
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