Cargando…

Mycobacterium tuberculosis Rv3463 induces mycobactericidal activity in macrophages by enhancing phagolysosomal fusion and exhibits therapeutic potential

Macrophages are responsible for innate and adaptive immune response activation necessary for eliminating infections. Optimal activation of macrophages to phagocytize Mycobacterium tuberculosis is critical in anti-mycobacterial defense. Here, we identified a novel Rv3463 hypothetical protein that ind...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Hye-Soo, Back, Yong Woo, Shin, Ki-Won, Bae, Hyun Shik, Lee, Kang-In, Choi, Han-Gyu, Choi, Seunga, Lee, Hwang-Ho, Choi, Chul Hee, Park, Jeong-Kyu, Kim, Hwa-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414722/
https://www.ncbi.nlm.nih.gov/pubmed/30862819
http://dx.doi.org/10.1038/s41598-019-38982-0