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Mycobacterium tuberculosis Rv3463 induces mycobactericidal activity in macrophages by enhancing phagolysosomal fusion and exhibits therapeutic potential
Macrophages are responsible for innate and adaptive immune response activation necessary for eliminating infections. Optimal activation of macrophages to phagocytize Mycobacterium tuberculosis is critical in anti-mycobacterial defense. Here, we identified a novel Rv3463 hypothetical protein that ind...
Autores principales: | Park, Hye-Soo, Back, Yong Woo, Shin, Ki-Won, Bae, Hyun Shik, Lee, Kang-In, Choi, Han-Gyu, Choi, Seunga, Lee, Hwang-Ho, Choi, Chul Hee, Park, Jeong-Kyu, Kim, Hwa-Jung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414722/ https://www.ncbi.nlm.nih.gov/pubmed/30862819 http://dx.doi.org/10.1038/s41598-019-38982-0 |
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