Identification of Amino Acid Residues in Influenza A Virus PA-X That Contribute to Enhanced Shutoff Activity

The influenza virus protein PA-X modulates the host immune responses and viral pathogenicity through suppression of host protein expression. The endonuclease active site in the N-terminal region, the basic amino acid cluster in the C-terminal PA-X-specific region, and N-terminal acetylation of PA-X...

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Detalles Bibliográficos
Autores principales: Oishi, Kohei, Yamayoshi, Seiya, Kawaoka, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414799/
https://www.ncbi.nlm.nih.gov/pubmed/30894843
http://dx.doi.org/10.3389/fmicb.2019.00432

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414799/
https://www.ncbi.nlm.nih.gov/pubmed/30894843
http://dx.doi.org/10.3389/fmicb.2019.00432

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