Photoluminescence Enhancement of Poly(3-methylthiophene) Nanowires upon Length Variable DNA Hybridization

The use of low-dimensional inorganic or organic nanomaterials has advantages for DNA and protein recognition due to their sensitivity, accuracy, and physical size matching. In this research, poly(3-methylthiophene) (P3MT) nanowires (NWs) are electrochemically prepared with dopant followed by functio...

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Detalles Bibliográficos
Autores principales: Huang, Jingyuan, Choi, Jinho, Lee, Gil Sun, Chen, Fengchun, Cui, Chunzhi, Jin, Long Yi, Park, Dong Hyuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414824/
https://www.ncbi.nlm.nih.gov/pubmed/30966135
http://dx.doi.org/10.3390/polym10010100
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author Huang, Jingyuan
Choi, Jinho
Lee, Gil Sun
Chen, Fengchun
Cui, Chunzhi
Jin, Long Yi
Park, Dong Hyuk
author_facet Huang, Jingyuan
Choi, Jinho
Lee, Gil Sun
Chen, Fengchun
Cui, Chunzhi
Jin, Long Yi
Park, Dong Hyuk
author_sort Huang, Jingyuan
collection PubMed
description The use of low-dimensional inorganic or organic nanomaterials has advantages for DNA and protein recognition due to their sensitivity, accuracy, and physical size matching. In this research, poly(3-methylthiophene) (P3MT) nanowires (NWs) are electrochemically prepared with dopant followed by functionalization with probe DNA (pDNA) sequence through electrostatic interaction. Various lengths of pDNA sequences (10-, 20- and 30-mer) are conjugated to the P3MT NWs respectively followed with hybridization with their complementary target DNA (tDNA) sequences. The nanoscale photoluminescence (PL) properties of the P3MT NWs are studied throughout the whole process at solid state. In addition, the correlation between the PL enhancement and the double helix DNA with various lengths is demonstrated.
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spelling pubmed-64148242019-04-02 Photoluminescence Enhancement of Poly(3-methylthiophene) Nanowires upon Length Variable DNA Hybridization Huang, Jingyuan Choi, Jinho Lee, Gil Sun Chen, Fengchun Cui, Chunzhi Jin, Long Yi Park, Dong Hyuk Polymers (Basel) Communication The use of low-dimensional inorganic or organic nanomaterials has advantages for DNA and protein recognition due to their sensitivity, accuracy, and physical size matching. In this research, poly(3-methylthiophene) (P3MT) nanowires (NWs) are electrochemically prepared with dopant followed by functionalization with probe DNA (pDNA) sequence through electrostatic interaction. Various lengths of pDNA sequences (10-, 20- and 30-mer) are conjugated to the P3MT NWs respectively followed with hybridization with their complementary target DNA (tDNA) sequences. The nanoscale photoluminescence (PL) properties of the P3MT NWs are studied throughout the whole process at solid state. In addition, the correlation between the PL enhancement and the double helix DNA with various lengths is demonstrated. MDPI 2018-01-20 /pmc/articles/PMC6414824/ /pubmed/30966135 http://dx.doi.org/10.3390/polym10010100 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Huang, Jingyuan
Choi, Jinho
Lee, Gil Sun
Chen, Fengchun
Cui, Chunzhi
Jin, Long Yi
Park, Dong Hyuk
Photoluminescence Enhancement of Poly(3-methylthiophene) Nanowires upon Length Variable DNA Hybridization
title Photoluminescence Enhancement of Poly(3-methylthiophene) Nanowires upon Length Variable DNA Hybridization
title_full Photoluminescence Enhancement of Poly(3-methylthiophene) Nanowires upon Length Variable DNA Hybridization
title_fullStr Photoluminescence Enhancement of Poly(3-methylthiophene) Nanowires upon Length Variable DNA Hybridization
title_full_unstemmed Photoluminescence Enhancement of Poly(3-methylthiophene) Nanowires upon Length Variable DNA Hybridization
title_short Photoluminescence Enhancement of Poly(3-methylthiophene) Nanowires upon Length Variable DNA Hybridization
title_sort photoluminescence enhancement of poly(3-methylthiophene) nanowires upon length variable dna hybridization
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414824/
https://www.ncbi.nlm.nih.gov/pubmed/30966135
http://dx.doi.org/10.3390/polym10010100
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