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Intranasal Application of Budesonide Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Suppressing Nucleotide-Binding Oligomerization Domain-Like Receptor Family, Pyrin Domain-Containing 3 Inflammasome Activation in Mice

AIM: To investigate the protective effects of budesonide against lipopolysaccharide- (LPS-) induced acute lung injury (ALI) in a murine model and its underlying mechanism. METHODS: Adult male C57BL/6 mice were divided into three groups: control, ALI, and ALI + budesonide groups. LPS (5 mg/kg) was in...

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Detalles Bibliográficos
Autores principales:	Dong, Liang, Zhu, Yu-Hang, Liu, De-Xing, Li, Juan, Zhao, Peng-Cheng, Zhong, Yuan-Ping, Chen, Yong-Qin, Xu, Wei, Zhu, Zhao-Qiong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415278/ https://www.ncbi.nlm.nih.gov/pubmed/30937316 http://dx.doi.org/10.1155/2019/7264383

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