WP1130 reveals USP24 as a novel target in T-cell acute lymphoblastic leukemia

BACKGROUND: T-cell acute lymphoblastic leukemia (T-ALL) is a lymphoid malignancy caused by the oncogenic transformation of immature T-cell progenitors with poor outcomes. WP1130 has shown potent activity against a variety of cancer but whether WP1130 has anti-T-ALL activity is not clear. USP24, one...

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Detalles Bibliográficos
Autores principales: Luo, Hao, Jing, Bo, Xia, Yu, Zhang, Yugen, Hu, Meng, Cai, Haiyan, Tong, Yin, Zhou, Li, Yang, Li, Yang, Junmei, Lei, Hu, Xu, Hanzhang, Liu, Chuanxu, Wu, Yingli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415346/
https://www.ncbi.nlm.nih.gov/pubmed/30911287
http://dx.doi.org/10.1186/s12935-019-0773-6

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