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Caveolin-3 KO disrupts t-tubule structure and decreases t-tubular I(Ca) density in mouse ventricular myocytes

Caveolin-3 (Cav-3) is a protein that has been implicated in t-tubule formation and function in cardiac ventricular myocytes. In cardiac hypertrophy and failure, Cav-3 expression decreases, t-tubule structure is disrupted, and excitation-contraction coupling is impaired. However, the extent to which...

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Detalles Bibliográficos
Autores principales:	Bryant, Simon M., Kong, Cherrie H. T., Watson, Judy J., Gadeberg, Hanne C., Roth, David M., Patel, Hemal H., Cannell, Mark B., James, Andrew F., Orchard, Clive H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Physiological Society 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415741/ https://www.ncbi.nlm.nih.gov/pubmed/30028203 http://dx.doi.org/10.1152/ajpheart.00209.2018

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